Hepatitis B testing, care linkage, and vaccination coverage within a registry of hepatitis C infected patients

Screening and Testing for Hepatitis B Virus Infection: CDC Recommendations — United States, 2023

“…In 10 U.S. studies, the prevalence of current HBV infection (on the basis of HBsAg positivity, HBV DNA positivity, or International Classification of Diseases, Tenth Revision codes) among persons with HCV infection ranged from 0.2% to 5.8% (median = 1.2%) (60-69). Among persons with HCV infection, the prevalence of ever being exposed to HBV ranged from 24.7% to 62.6% (median = 43.0%); this finding was based on anti-HBc positivity, regardless of other HBV test results (62)(63)(64)(65)69,70). Isolated anti-HBc positivity ranged from 36.9% to 53.8% (median = 39.5%) among patients with HCV infection (62,65,69).…”

“…Among persons with HCV infection, the prevalence of ever being exposed to HBV ranged from 24.7% to 62.6% (median = 43.0%); this finding was based on anti-HBc positivity, regardless of other HBV test results (62)(63)(64)(65)69,70). Isolated anti-HBc positivity ranged from 36.9% to 53.8% (median = 39.5%) among patients with HCV infection (62,65,69).…”

Improved hepatitis A and hepatitis B vaccination strategy is necessary for patients with chronic hepatitis C

“…Despite recommendations from ACIP and CDC, the HBV-immunization rate for chronic hepatitis C patients is suboptimal [ 6 ]. Harris et al [ 7 ] reported that only 55% of HCV patients had complete HBV serological testing at an urban health system and 27% remained susceptible to HBV infection. Our results showed a similar trend with a 68% HBV-testing rate and 38% HBV-susceptible at referral.…”

“…Only about 20% of the patients with HBV-vaccine response had cirrhosis. Reduced vaccine response among patients with advanced liver disease could also be a contributing factor [ 7 ]. A large proportion of the HCV patients susceptible for HBV infection in this study had cirrhosis and were >40 years of age; these patients would also have poor liver-disease prognosis if they acquired HBV coinfection [ 8 ].…”

Avaliação da imunogenicidade anti-HBV em portadores crônicos do vírus da hepatite C não cirróticos após exposição a dois esquemas de vacina contra hepatite B

“…A importância do conhecimento da prevalência do AgHBs em certas áreas geográficas, auxilia tanto no conhecimento do mais eficiente modo de transmissão das regiões, quanto no melhor direcionamento e implementação das políticas públicas de saúde de conscientização e imunização [38][39] .…”