Hepatitis B virus (HBV) markers among patients with chronic liver disease in Kuwait

Al‐Nakib, Basil; Al‐Nakib, W.; Bayoumi, Ahmed; H, Al-Liddawi; Bashir, A. A.

doi:10.1016/0035-9203(82)90187-0

Cited by 11 publications

(3 citation statements)

References 6 publications

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“…The results were not uniform, some of them showing association between B virus and schistosomiasis 2,19,20,37,52,61 , while others did not demonstrated a higher prevalence 27,28,40,73 or a higher rate of chronification of hepatitis 69 .…”

Section: Introductionmentioning

confidence: 81%

Hepatitis B and C virus markers among patients with hepatosplenic mansonic schistosomiasis

Aquino¹,

Chieffi

Catunda³

et al. 2000

Rev. Inst. Med. trop. S. Paulo

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SUMMARYPurpose: To evaluate the frequency and the consequences of the co-infection of hepatitis B and C viruses in patients with hepatosplenic schistosomiasis (HSS).Methods: B and C serologic markers, exposure to risk factors, biochemical assays, upper gastrointestinal endoscopies, and abdominal ultrasonograms were evaluated in 101 patients with HSS from 1994 to 1997. Whenever possible, PCR was tested and histopathological studies were reviewed.Results: At least one HBV virus marker was found in 15.8%, and anti-HCV was detected in 12.9% of the subjects. The seropositive subjects tended to be older than the seronegative ones. A history of blood transfusion was significantly related to the presence of anti-HCV. Three (18.75%) out of 16 subjects exposed to B virus were HBsAg positive. Eleven (84.6%) out of thirteen patients who were anti-HCV positive demonstrated viral activity. Patients with ongoing viral infection presented a higher average level of liver aminotransferases, a higher frequency of cell decompensation and a higher rate of chronic hepatitis. Portal hypertension parameters were not influenced by viral exposure. Conclusions:The rate of hepatitis B and C viruses serologic markers observed in the patients with HSS was higher than the control group. The co-infection was responsible for a higher frequency of cell decompensation.

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Section: Introductionmentioning

confidence: 81%

Hepatitis B and C virus markers among patients with hepatosplenic mansonic schistosomiasis

Aquino¹,

Chieffi

Catunda³

et al. 2000

Rev. Inst. Med. trop. S. Paulo

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“…4 in Fez, 53.7% in Tunisia, 17 45% in an English study 18 made by Gennaro Amico collected 118 cirrhotic patients and a rate ranged from 65.5% to 71.4% according to a sub-Saharan African series. 19,20 where ascites was cited as the first reason for revealing the disease. Doppler ultrasound and possibly CT and magnetic resonance imaging can be used to diagnose and specify the type of portal hypertension, but the results of these methods can not be used to accurately assess the degree of portal hypertension importance.There is no correlation between the degree of portal hypertension and the portal vein diameter, but there is a negative correlation between the hepatic pressure gradient and blood flow in the portal vein.…”

Section: Discussionmentioning

confidence: 99%

Portal hypertension: monocentric retrospective study of 387 cases and review of the literature

Bellouhou¹,

Haddar²,

Errami³

et al. 2021

GHOA

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The portal hypertension is one of the major complications of cirrhosis. It causes hemorrhages by rupture of oesophageal varices and contributes to the development of ascites and hepatic encephalopathy. This is a retrospective study collecting 387 cases of portal hypertension diagnosed at the service of Hepato-gastroenterology of Mohamed VI University Hospital of Marrakech between January 2014 and December 2018.The purpose of this work is to determine the epidemiological aspects, clinico -biological, radiological, endoscopic and therapeutic of portal hypertension and its complications. The average age was 51.3years, the sex ratio M/F was 0.8. Portal hypertension was revealed by haemorrhagic decompensation in 48.8% of cases, ascitic decompensation in 53.2% of cases, splenomegaly in 47.8% of cases, jaundice in 27.13% of cases, and hepatic encephalopathy in 8.52% of cases. Almost half of the cirrhotic patients were classified as child B. Upper digestive endoscopy objectified esophageal varices in the majority of patients, gastric varices in almost one-third of cases. Cirrhosis was the most common etiology of portal hypertension in 86.82%, cirrhosis post viral was reported in 28.57% of cases. The alcoholic origin of cirrhosis was objectified in only 5.76% of cases. Nearly two-thirds of patients had ascitic decompensation, half of them haemorrhagic decompensation and 11.6% had hepatic encephalopathy. Hepatic hydrothorax was observed in 9.81% of cases, and hepatocellular carcinoma in 6.20% (n=24) of cases.

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“…The included 99 studies were in English language and covered the period from 1981 to 2020. Detailed summary of studies' characteristics is shown in Additional file 2: Appendix C. Most studies were performed in KSA (n = 75) [10,, followed by Kuwait (n = 5) [92][93][94][95][96], UAE (n = 5) [97][98][99][100][101], Oman (n = 5) [102][103][104][105][106], Qatar (n = 4) [107][108][109][110] and finally Bahrain (n = 3) [111][112][113]. There was one study that was performed in both Bahrain and KSA [114] and another that included Oman, UAE and Qatar [115].…”

Section: Study Characteristicsmentioning

confidence: 99%

Prevalence of Hepatitis B Virus infection in the Gulf Cooperation Council: a systematic review and meta-analysis

Alali

Abo‐Shehada

2022

BMC Infect Dis

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Background Hepatitis B virus (HBV) infection is a global public-health problem. Since the introduction of an effective vaccine, the epidemiology of HBV infection is changing. We aimed to estimate the prevalence of HBV infection in the Gulf Cooperation Council (GCC) region and delineate any variation in member-countries, special sub-groups, and over time. Methods This is a systematic review and meta-analysis to review studies of HBV prevalence in the GCC region. Databases were searched and all studies from inception to July 31st, 2021, were considered for inclusion. The pooled HBV prevalence was analyzed using the random-effect model after assessment for heterogeneity. True prevalence was adjusted using the Rogan-Gladen estimator. Pre-defined subgroup analysis was performed, and publication bias was assessed. Results Overall, 99 studies (n = 1,944,200 participants) met the inclusion criteria. The overall HBV apparent prevalence was 3.05% (95% CI 2.60, 3.52) and the true prevalence was 1.67% (95% CI 1.66, 1.68). The apparent prevalence varied between subgroups. Over time, the apparent prevalence of HBV infection has declined from 9.38% (95% CI 7.26, 11.74) before 1990 to 1.56% (95% CI 1.07, 2.12) during the period 2010 to 2020. Conclusion Over the last four decades the overall prevalence of HBV infection in the GCC region has decreased from high- to low-endemicity level. However, due to poor methodology of the included studies, further high-quality community-based studies are needed to obtain more precise estimate of HBV infection in this region.

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Hepatitis B virus (HBV) markers among patients with chronic liver disease in Kuwait

Cited by 11 publications

References 6 publications

Hepatitis B and C virus markers among patients with hepatosplenic mansonic schistosomiasis

Hepatitis B and C virus markers among patients with hepatosplenic mansonic schistosomiasis

Portal hypertension: monocentric retrospective study of 387 cases and review of the literature

Prevalence of Hepatitis B Virus infection in the Gulf Cooperation Council: a systematic review and meta-analysis

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