2019
DOI: 10.21203/rs.2.13291/v1
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HER2 expression and relevant clinicopathological features in esophageal squamous cell carcinoma in a Chinese population

Abstract: Background: Despite great progress of surgery and other treatments, the prognosis of patients with esophageal squamous cell carcinoma (ESCC) is still very poor. HER2 has strong therapeutic implications in certain cancers, such as breast cancer and gastric cancer. However, literature on the frequency of HER2 expression in ESCC is scarce. In the present study, HER2 expression and gene amplification and the association of HER2 status with clinicopathological characteristics were evaluated in a large cohort of Chi… Show more

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