“…Cancer chemoprevention [57,58] has become an important therapeutic option through which the battle against cancer could be possible, using natural, synthetic or biological agents able to reverse, suppress or prevent either carcinogenesis or the progression of premalignant cells towards invasive tumors. For this purpose, plants and herbs may be a promising source for adjuvant, complementary or alternative anti-cancer therapy [59,60,61,62,63,64,65,66,67,68], since some of them contain bioactive natural products and anti-cancer compounds, including polyphenols [32,33,69,70] as flavonoids, tannin etc. Today, many phytochemical compounds, normally biosynthesized and accumulated in the plants, have shown chemopreventive actions and several anti-cancer drugs, including podophilotoxins, camptotoxins, taxans, arise from herbal compounds and are successfully used for anti-cancer therapy [63,71].…”