2019
DOI: 10.1093/jamiaopen/ooz035
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Heterogeneity introduced by EHR system implementation in a de-identified data resource from 100 non-affiliated organizations

Abstract: Objectives Electronic health record (EHR) data aggregated from multiple, non-affiliated, sources provide an important resource for biomedical research, including digital phenotyping. Unlike work with EHR data from a single organization, aggregate EHR data introduces a number of analysis challenges. Materials and Methods We used the Cerner Health Facts data, a de-identified aggregate EHR data resource populated by data from 10… Show more

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Cited by 36 publications
(24 citation statements)
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“…The descriptive and predictive multicenter models developed in this study were built using a subset of data from the database based on a priori inclusion criteria. An extensive analysis of a prior version of the database has been conducted with recommendations on its use [25].…”
Section: Study Design and Settingmentioning
confidence: 99%
“…The descriptive and predictive multicenter models developed in this study were built using a subset of data from the database based on a priori inclusion criteria. An extensive analysis of a prior version of the database has been conducted with recommendations on its use [25].…”
Section: Study Design and Settingmentioning
confidence: 99%
“…A challenge inherent in this and all pediatric studies of chronic abdominal pain is the inconsistencies in diagnosing specific AP-FGIDs. The strength of the current study is that the database allowed for the description of costs across a large population drawn from multiple sites and across the continuum of care with wide geographic distribution [22,23]. Utilizing the Health Facts database allowed for evaluation across centers and across the continuum of care including outpatient, emergency department, and inpatients settings.…”
Section: Discussionmentioning
confidence: 99%
“…Additionally, as our analysis was focused on potential associations to the least and most adherent subcohort, we did not include the second and third quartile facilities (NA-1 nor NA-4) despite a significant number of patients. Another possible limitation is that some A1c tests may not be included in HF due to the absence of the Cerner laboratory module at some sites or the use of point-of-care A1c testing that does not populate the pathology database tables [ 40 ]. Also, the same concerns may apply to our observation of limited ordering of fructosamine and the absence of other alternative tests.…”
Section: Discussionmentioning
confidence: 99%