Heterogeneous palladium (II)‐complexed dendronized polymer: A rare palladium catalyst for the one‐pot synthesis of 2‐arylbenzoxazoles

Abstract

The palladium complex of dendronized amine polymer (EG-Gn-Pd, n = 0, 1 and 2) having ethylene glycol-initiated polyepichlorohydrin as core was synthesized on a Merrifield resin support and was well characterized. Generally, palladium catalysts are known for carbon-carbon coupling reactions. Here, a developed catalyst was found to be good for benzoxazole synthesis. Higher generation dendronized polymer (EG-G2-Pd) was found to be better catalyst over lower generation dendronized polymers. Moreover, dendronized polymers were found to be a better catalyst over dendrigraft polymers. The catalyst reusability was checked and good yield was obtained for five cycles.

Advances in the synthetic strategies of benzoxazoles using 2-aminophenol as a precursor: an up-to-date review

“…In 2020, George and Sreekumar 52 prepared palladium complexes of dendronized amine polymer (EG–G n –Pd, n = 0, 1, and 2) catalysts for the synthesis of benzoxazoles ( 3 ). The reaction between 2-aminophenol ( 1 ) and benzaldehyde ( 2 ) with an EG–G2–Pd catalyst (10 mg) in ethanol at 50 °C for 3 h gave 88% product yield.…”

Nanocatalyzed Synthesis of Benzoxazoles

“…In this scenario, we mainly highlighted the synthesis of benzoxazoles and their derivatives using nanocatalyst materials. Additionally, focus on benzoxazoles′ substantial significance because of their phenomenal therapeutic functions like cyclooxygenase inhibitors, anti‐HIV, anticancer, antibiotics, antifungals, antivirals, anticonvulsant agents, antioxidants, antitumors, antiulcers, antibacterials, anti‐inflammatory, anti‐tubercular, and analgesics., [15,16] The majority of benzoxazole compounds have significant uses in materials science, such as electronic devices and sensors for metals, as well as their use as photoluminescent dyes, photochromatic agents, and laser dyes [17] . Moreover, polymer industries, fluorescent brighteners, [18] optical brighteners in laundry detergents are also increasingly important in agrochemicals [19,20] .…”