Heterotopic Tissue in Lymph Nodes

Sawicki, Mark; Howard, Thomas J.; Passaro, Edward

doi:10.1001/archsurg.1990.01410220178025

Cited by 6 publications

(2 citation statements)

References 38 publications

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“…Carcinoma may also arise in ectopic breast tissue within the axilla, or ectopic breast tissue within a lymph node [13]. The latter may be very difficult to demonstrate because the tumour growth usually obliterates the glandular tissue at a very early stage [14].…”

Section: Discussionmentioning

confidence: 99%

Clinical experience with axillary presentation breast cancer

Galimberti

Bassani

Monti

et al. 2004

Breast Cancer Res Treat

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We present our experience of 50 cases of occult primary tumours presenting as axillary metastases, all with histological report of adenocarcinoma compatible with mammary carcinoma. After bilateral US and mammography, with MRI and mammoscintigraphy where necessary, ipsilateral breast cancer was suspected in 23 cases and quadrantectomy performed. Breast cancer was found only in 12 (24%). In the other 27 women there was no clinical or instrumental suspicion of breast cancer or other primary disease site, so the main treatment was complete axillary dissection plus radiotherapy to the ipsilateral breast (given to all patients). Chemotherapy alone was given to 27 patients, hormone treatment to 5 patients, and both to 18. Mean follow-up is 41.3 months (range 108-1). Thirty-nine (84%) patients are alive with no evidence of disease, two are alive with breast disease, five patients have died of metastatic disease (with no evidence breast disease). Our experience, like that of the literature, confirms that the breast should be extensively investigated but that blanket investigations are not usually revealing. We present guidelines for the work-up of patients presenting with axillary disease.

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Section: Discussionmentioning

confidence: 99%

Clinical experience with axillary presentation breast cancer

Galimberti

Bassani

Monti

et al. 2004

Breast Cancer Res Treat

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“…However, the existence of heterotopic thyroid tissue within cervical glands has been reported. Six such cases of normal thyroid gland at 5-Ìm sections were described by Sawicki et al [4]. The final morphologic expression of laterally aberrant thyroid tissue must be termed congenital.…”

Section: Discussionmentioning

confidence: 99%

Ectopic Thyroid Tissue Masquerading as a Lateral Neck Mass: A Case Report

et al. 2011

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The tissue bud that ultimately becomes the thyroid gland arises initially as a midline diverticulum in the floor of the pharynx. When the median thyroid analage does not descend in normal fashion, a lingual thyroid can result. It is thought that any thyroid tissue found in the lateral aspect of the neck, including around the vascular structures of the neck, may represent metastatic deposits from well-differentiated thyroid carcinoma. This is a case report of a 35 year old male presenting to the out-patient department with a swelling in the lateral aspect of the neck. The MRI report showed an enlarged level 2 lymph node in the lateral aspect of right side of the neck for which surgery was done and the specimen sent for HPE. Histopathological report gave a surprising report of thyroid tissue with normal follicular cells. But literature says that thyroid tissue lateral to the normal thyroid tissue is essentially metastatic papillary carcinoma. Only very few previous case reports showing the existence of ectopic thyroid in the lateral aspect of the neck have been documented (1,2,3). This case has been reported for its rarity.

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