Hibiscus sabdariffa extract reduces serum cholesterol in men and women

Lin, Tzu-Li; Lin, Hui-Hsuan; Chen, Chang-Che; Lin, Ming‐Cheng; Chou, Ming‐Chih; Wang, Chau‐Jong

doi:10.1016/j.nutres.2007.01.007

Cited by 128 publications

(89 citation statements)

References 35 publications

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“…Roselle (Hibiscus sabdariffa L.) on the other hand belongs to the Family Malvaceae and is known in Nigeria as "Zobo". It is used effectively in folk medicines for the treatment of hypertension, inflammatory diseases and cancer (Kong et al, 2003;Lin et al, 2007), decrease blood viscosity and reduce hypertension (Christian et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

Health promoting properties of Alternanthera brasiliana leaves and Hibiscus sabdariffa calyces used in fortification of maize-bambara groundnut malt and maize-cowpea malt complementary foods

Attaugwu¹,

Uvere²

2017

Food Res.

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The study evaluated the chemical and antioxidant properties of Alternanthera brasiliana leaves and Hibiscus sabdariffa calyces used in iron and zinc fortification of maizebambara groundnut malt and maize-cowpea malt complementary foods. A. brasiliana and H. sabdariffa extracts had concentration-dependent DPPH activity with IC 50 of 1.76 mg/ml and 5.745 mg/ml, nitric oxide scavenging activity with IC 50 of 0.675 mg/ml and 3.976 mg/ml while the ferric reducing power had an absorbance range of 0.5 -0.982 and 0.959 -0.986 respectively. The study revealed that A.brasiliana leaves and H. sabdariffa calyces contain components that will impact positively on the health of the infants when used to formulate complementary foods.

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Section: Introductionmentioning

confidence: 99%

Health promoting properties of Alternanthera brasiliana leaves and Hibiscus sabdariffa calyces used in fortification of maize-bambara groundnut malt and maize-cowpea malt complementary foods

Attaugwu¹,

Uvere²

2017

Food Res.

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“…The plant is also reported to be antiseptic, astringent, cholagogue, demulcent, digestive, purgative and resolvent. It is used as a folk remedy in the treatment of abscesses, bilious conditions, cancer, cough, debility, dyspepsia, fever, hangover, heart ailments; and hypertension (Vilasinee et al, 2005;Lin et al, 2007). The calyces of HS are prolific in many modern commercial blends of cold and hot drinks due to its pleasing taste, as well as having decorative, culinary and medicinal uses (Ngamjarus et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

The Effect of Ethanolic Extract of Hibiscus sabdariffa on some Physiological and Antioxidant Parameters in Female Rabbits

Ali¹,

Abdul-Azeez²,

Humood³

et al. 2016

J. Anim. Health Prod.

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| The aim of this study was to investigate the effects of ethanolic extract of 70% Hibiscus sabdariffa (HS) on some physiological parameters and the alteration in enzymatic and non-enzymatic antioxidants in female rabbits. Ten female adult rabbits were divided into two groups (5 rabbits/group), group1: Control group received orally normal saline for four weeks, group2: the treated group received (200 mg/Kg) B.W of the ethanolic extract of HS. Blood samples were collected from animals by cardiac puncture technique. At the end of experiment the results showed that there were significant increase in red blood cell count (RBCC), hemoglobin concentration (Hb) with significant decrease in platelet count (Plt) and non-significant increase in the white blood cell count (WBCC), lymphocyte, monocyte and significant increase in granulocyte count in animals treated by HS extract as compared with control group. The results of liver enzymes showed that there were non-significant increase in activity of serum aspartate aminotransferase (AST), alkaline phosphatase (ALP), and non-significant decrease in serum alanine aminotransferase (ALT) in HS extract treated group as compared with the control group. The results of kidney function parameters explained that there were non-significant increase in level of urea but there were significant (p < 0.05) decrease in level of uric acid in animals treated with HS as compared with control. Moreover, the results of this study showed that there were significant (p < 0.05) decrease in serum triacylglycerol (TAG), cholesterol, superoxide dismutase (SOD), glutathione peroxidase (GPx), but there was non-significant (p > 0.05) changes in catalase activity (CAT), malondialdehyde (MDA), glutathione (GSH), vitamin E (Vit E), and vitamin C (Vit C). The results obtained from this study explained that 70% ethanolic extract of HS increase (RBCC) count, enhance immunity by increasing granulocyte count, and had hypolipidemic and antioxidant effect in female rabbit. Keywords

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“…9,10 Different studies, both in animal [11][12][13][14] and human models, 15,16 have shown that an extract or infusion of ST influences the atherosclerosis process, blood sugar and lipids, and BP. Lin et al 17 reported that ST infusion reduces cholesterol by 8.3-14.4% after 4 weeks. 18 Chen et al 19 showed that ST extracts reduce triglyceride, cholesterol, low-density lipoprotein cholesterol (LDLc) and LDLc/HDLc in hyperlipidaemic rats.…”

Section: Introductionmentioning

confidence: 99%

The effects of sour tea (Hibiscus sabdariffa) on hypertension in patients with type II diabetes

et al. 2008

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To compare the antihypertensive effectiveness of sour tea (ST; Hibiscus sabdariffa) with black tea (BT) infusion in diabetic patients, this double-blind randomized controlled trial was carried out. Sixty diabetic patients with mild hypertension, without taking antihypertensive or antihyperlipidaemic medicines, were recruited in the study. The patients were randomly allocated to the ST and BT groups and instructed to drink ST and BT infusions two times a day for 1 month. Their blood pressure (BP) was measured on days 0, 15 and 30 of the study. The mean of systolic BP (SBP) in the ST group decreased from 134.4 ± 11.8 mm Hg at the beginning of the study to 112.7 ± 5.7 mm Hg after 1 month (P-value o0.001), whereas this measure changed from 118.6 ± 14.9 to 127.3 ± 8.7 mm Hg (P-value ¼ 0.002) in the BT group during the same period. The intervention had no statistically significant effect on the mean of diastolic BP (DBP) in either the ST or BT group. The mean pulse pressure (PP) of the patients in the ST group decreased from 52.2±12.2 to 34.5±9.3 mm Hg (P-value o0.001) during the study, whereas in the BT group, it increased from 41.9 ± 11.7 to 47.3 ± 9.6 mm Hg (P-value ¼ 0.01). In conclusion, consuming ST infusion had positive effects on BP in type II diabetic patients with mild hypertension. This study supports the results of similar studies in which antihypertensive effects have been shown for ST.

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Hibiscus sabdariffa extract reduces serum cholesterol in men and women

Cited by 128 publications

References 35 publications

Health promoting properties of Alternanthera brasiliana leaves and Hibiscus sabdariffa calyces used in fortification of maize-bambara groundnut malt and maize-cowpea malt complementary foods

Health promoting properties of Alternanthera brasiliana leaves and Hibiscus sabdariffa calyces used in fortification of maize-bambara groundnut malt and maize-cowpea malt complementary foods

The Effect of Ethanolic Extract of Hibiscus sabdariffa on some Physiological and Antioxidant Parameters in Female Rabbits

The effects of sour tea (Hibiscus sabdariffa) on hypertension in patients with type II diabetes

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