hiC sequencing v1

Abstract

The golden apple snail (Pomacea canaliculata) is a fresh water snail listed among the top-100 worst invasive species, worldwide and a noted agricultural and quarantine pest that causes great economic losses. It is characterized by fast growth, strong stress tolerance, a high reproduction rate, and adaptation to a broad range of environments.Here, we used long-read sequencing to produce a 440-Mb high-quality chromosome-level assembly for the P. canaliculata genome. In total, 50 Mb (11.4%) repeat sequences and 21,533 gene models were identified in the genome. The major findings of this study include the recent explosion of DNA/hAT-Charlie transposable elements (TEs), the expansion of the P450 gene family and the constitution of the cellular homeostasis system, which contributes to ecological plasticity in stress adaptation. In addition, the high transcriptional levels of perivitellin genes in the ovary and albumen gland promote the function of nutrient supply and defence ability in eggs. Furthermore, the gut metagenome also contains diverse genes for food digestion and xenobiotic degradation.

Mesenchymal stem cell therapy for neurological disorders: The light or the dark side of the force?

“…Similar results with miR-29benriched EVs were also obtained by Jahangard et al in rat AD models (Jahangard et al, 2020). On top of miR-29, studies have also shown beneficial effects of miR-21, miR-22, miR-1246, wherein these miRNAs slowed cognitive deterioration in AD mice through regulation of neuroinflammation and synaptic damage (Cui et al, 2018;Cone et al, 2021). With that, in order to optimize miR cargo delivery and, therewith, develop novel AD treatments, one must first understand the intricate connection between progression of AD and exo-miRs (Zeng et al, 2022).…”

Progress and potential for symmetrical solid oxide electrolysis cells

“…152 Therefore, curbing NOx pollution has been a universal issue and various NOx removal technologies have been developed. [153][154] SSOEC with LSM/GDC electrode was adopted to electrochemical catalytic reduction of NO. 155 BaO and Pt were infiltrated to electrodes in order to further improve the catalytic activity.…”

High vagally mediated resting-state heart rate variability is associated with superior working memory function

“…It is widely used as a safe, non-invasive, and reliable diagnostic tool to quantitatively analyze cardiovascular autonomic function (Zeki Al Hazzouri et al, 2018). HRV parameters can be obtained through time-domain, frequency-domain and non-linear analyses (Chan et al, 2015). On this basis, researchers can acquire some indicators underlying physiological mechanisms.…”