Hidradenitis Suppurativa: An Update

Lee, Robert A.; Yoon, Andrew; Kist, Joseph M.

doi:10.1016/j.yadr.2007.07.001

Cited by 19 publications

(30 citation statements)

References 94 publications

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“…To our knowledge, involvement of face and/or back has not been described previously. In a recent review article however, Lee et al [12] presented a clinical photograph of the back of a patient with HS lesions. There are no apocrine glands in these territories, but we know that the apocrine gland is not the primary target in HS [13,14].…”

Section: Discussionmentioning

confidence: 99%

Back and Face Involvement in Hidradenitis Suppurativa

Poli

Wolkenstein

Revuz³

2010

Dermatology

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Background: Hidradenitis suppurativa (HS) may be associated with face and back lesions which are considered as acne. Objective: To describe the skin lesions of a group of patients with HS. Methods: Twelve patients were selected from a series of 648 patients on the basis of their specific skin lesions. Results: The patients (mostly male) had typical hidradenitis. On their face or back they had one or several of the following skin lesions which are not seen in acne: hypertrophic rope-like bridged scars, raised plaques with multiple carbuncle-like openings or with ulcerations, ‘worm-eaten scars’ and coalescent nodules with round ulcerations. All patients had deep round scars. Several had a pilonidal cyst or large epidermal cysts. Isotretinoin had been used by 7 patients with no effect. Conclusion: Some HS patients have specific lesions of the face and back which are not acne and have to be treated differently.

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Section: Discussionmentioning

confidence: 99%

Back and Face Involvement in Hidradenitis Suppurativa

Poli

Wolkenstein

Revuz³

2010

Dermatology

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“…Antibiotic therapy for HS may be administered topically or systemically. 161 Clindamycin is the best-studied of the topical medications. A randomized controlled trial was conducted with 27 patients who used topical clindamycin 1% solution twice daily for 12 weeks.…”

Section: Antibioticsmentioning

confidence: 99%

Hidradenitis suppurativa: A comprehensive review

Alikhan

Lynch²,

Eisen³

2009

Journal of the American Academy of Dermatology

602

636

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“…These are used extensively for HS/AI despite few studies on efficacy [31]. They treat the inflammatory epiphenomena of HS, not the cause.…”

Section: Antibioticsmentioning

confidence: 99%

Hidradenitis suppurativa

Margesson

Danby

2014

Best Practice & Research Clinical Obstetrics & Gynaecol

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Hidradenitis suppurativa is a chronic relapsing disorder of the folliculopilosebaceous units (FPSUs). Its negative impact on quality of life is extreme, mainly due to the lack of early recognition, accurate diagnosis, and appropriate management. The support structure of the FPSUs is defective. Under the influence of endogenous reproductive hormones, exogenous hormones, androgens and their precursors in dairy products, and other dietary factors, the follicular unit is plugged and distended by retained keratin. Friction, shearing forces, and pressure lead to rupture and leakage of the ductal contents from the weakened FPSU, causing an inflammatory reaction mediated mainly by the innate immune system. Therapy requires patient comprehension and cooperation, counseling, aggressive hormonal and dietary modification, avoidance of the trauma that leads to rupture, active multimodal anti-inflammatory therapy, and early unroofing and debridement. The full therapeutic program is needed to avoid the aggressive surgery required if the condition is not diagnosed early and managed appropriately.

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Hidradenitis Suppurativa: An Update

Cited by 19 publications

References 94 publications

Back and Face Involvement in Hidradenitis Suppurativa

Back and Face Involvement in Hidradenitis Suppurativa

Hidradenitis suppurativa: A comprehensive review

Hidradenitis suppurativa

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