Hidradénome nodulaire malin et hidradénomes nodulaires multiples chez un malade hypogonadique

A, Toulemonde; Croué, Anne; Rodien, Patrice; Verret, J L

doi:10.1016/s0151-9638(06)71088-2

Cited by 13 publications

(7 citation statements)

References 19 publications

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“…Elle survient préférentiellement au niveau de la tête et du cou [3], rarement au niveau des membres. Le diagnostic de certitude est basé sur l'étude anatomopathologique qui montre une prolifération tumorale intradermique en nappe, comportant une différenciation sudorale et découpée par un stroma dense et hyalinisé avec pléomorphisme nucléaire et figures de mitoses[4, 5]. La chirurgie basée sur une exérèse large avec des limites saines est le gold standard [7, 11, 12].…”

Section: Discussionunclassified

“…Elle survient préférentiellement au niveau de la tête et du cou [3], rarement au niveau des membres. Le diagnostic histopathologique de malignité se fait sur des critères architecturaux et cytologiques particuliers [4, 5]. L'excision chirurgicale large représente l'essentiel du traitement, pourtant et vu le risque élevé de récidives locales allant de 10 à 50% [6] ; une radiothérapie adjuvante s'avère nécessaire dans plusieurs cas [7].…”

Section: Introductionunclassified

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Hidradénocarcinome du cuir chevelu : à propos d’un cas

Sbai¹,

Ouabdelmoumene²,

Naciri³

et al. 2014

Pan Afr Med J

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L'hidradénocarcinome est une tumeur annexielle maligne extrêmement rare. Caractérisée par la fréquence des récidives locorégionales et des métastases à distance. Le diagnostic histopathologique de malignité se fait sur des critères architecturaux et cytologiques particuliers .la chirurgie d'exérèse large représente l'essentiel du traitement. Une radiothérapie adjuvante s'avère obligatoire en cas de facteurs de récidive locale. Le curage ou la radiothérapie prophylactiques des aires ganglionnaires régionales non envahies pourraient jouer un rôle primordial dans la réduction du risque de récidives locorégionales.

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Section: Discussionunclassified

Section: Introductionunclassified

Hidradénocarcinome du cuir chevelu : à propos d’un cas

Sbai¹,

Ouabdelmoumene²,

Naciri³

et al. 2014

Pan Afr Med J

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“…HDC has been described for the first time by Keasby and Hadley in 1954[3], even today fifty cases have been reported in the literature[4]. It is a rare tumor reported most frequently on the head and neck and rarely on the distal extremities; the mean age of onset is 50 years, with a slight female predominance[5].…”

Section: Discussionmentioning

confidence: 99%

“…HDC usually present as a nodule, painless, firm or cystic, sometimes leaving a liquid which is serous or hemorrhagic. This nodule is usually single, and slowly growing[4]. The diagnosis is based on histopathological examination after biopsy or surgery, showing sweat intradermal proliferation inside a dense hyalinized stroma with nuclear pleomorphism and figures of mitosis[45], necrosis is common[5].…”

Section: Discussionmentioning

confidence: 99%

Radiotherapy on hidradenocarcinoma

Lalya

Hadadi

Tazi³

et al. 2011

North Am J Med Sci

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Context:Clear cell Hidradenocarcinoma is a rare carcinoma arising from sweat glands. It is an aggressive tumor that most metastasizes to regional lymph nodes and distant viscera; surgery with safe margins is the mainstay of treatment.Case Report:We report a case of 68-year-old woman who presented with an invasive clear cell hidradenocarcinoma situated in the left parotid area which recurred 5 months after surgery, this recurrence was managed successfully by high-dose irradiation of the tumor bed (66 Gy) and regional lymphatic chains (50 Gy), after a follow-up of more than 15 months, the patient is in good local control without significant toxicity.Conclusion:Post operative radiotherapy allows better local control and should be mandatory when histological features predictive of recurrence are present: positive margins, histology poorly differentiated, perineural invasion, vascular and lymphatic invasion, lymph node involvement, and extracapsular spread.

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“…This rare malignancy presents initially and/or most frequently on the head and neck region especially on the face [ 6 , 7 ]. The diagnosis is based on histological and immunohistochemical analysis [ 8 , 9 ]. Hidradenocarcinoma should be differentiated from several benign tumours like hemangiomas, lipomas, and lymphangiomas; and malignant tumours like malignant melanoma, basal cell carcinomas, squamous cell carcinomas, and [ 10 ] other malignant adnexal carcinomas [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

Current management approach to hidradenocarcinoma: a comprehensive review of the literature

Soni

Bansal

Kaushal

et al. 2015

ecancer

109

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Hidradenocarcinoma is a rare malignant adnexal tumour which arises from the intradermal duct of eccrine sweat glands. The head and neck are the most common sites of hidradenocarcinoma, but rarely it can occur on the extremities. As it is an aggressive tumour, regional lymph nodes and distant viscera are the most common sites of metastasis. Diagnosis is confirmed by histopathology and immunohistochemistry. Hidradenocarcinoma should be differentiated from benign and malignant adnexal tumours. Being an aggressive and rare tumour, no uniform treatment guidelines have been documented so far for metastatic hidradenocarcinoma. Wide local excision is the mainstay of the treatment, but because of high local recurrence, radiotherapy in a dose of 50Gy–70Gy and/or 5-fluorouracil and capecitabine-based combination chemotherapy may be given to further improve local control. Other treatment strategies are targeted therapies like trastuzumab, EGFR inhibitors, PI3K/Akt/mTOR pathway inhibitors, hormonal agents like antiandrogens, electrochemotherapy, or clinical trials.

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Hidradénome nodulaire malin et hidradénomes nodulaires multiples chez un malade hypogonadique

Cited by 13 publications

References 19 publications

Hidradénocarcinome du cuir chevelu : à propos d’un cas

Hidradénocarcinome du cuir chevelu : à propos d’un cas

Radiotherapy on hidradenocarcinoma

Current management approach to hidradenocarcinoma: a comprehensive review of the literature

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