High blood pressure variability predicts 30-day mortality but not 1-year mortality in hospitalized elderly patients

Weiss, Avraham; Rudman, Yaron; Beloosesky, Yichayaou; Akirov, Amit; Shochat, Tzippy; Grossman, Alon

doi:10.1080/08037051.2017.1300859

Cited by 3 publications

(6 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Currently, there are no guidelines as to what constitutes a Bsafe^discharge SBP. 1,3,4 In our study, a discharge SBP of 110-140 mmHg was associated with the lowest odds of adverse events in the 30 days post-hospitalization. The odds of 30-day mortality/readmission increased at SBPs < 110 mmHg-with the highest odds observed at SBP values < 80 mmHg.…”

Section: Discussionsupporting

confidence: 47%

Association of Final Discharge Blood Pressure with Post-discharge Outcomes Using Electronic Medical Record Data: a Retrospective Study

Khambaty

Sahni

2019

J GEN INTERN MED

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 47%

Association of Final Discharge Blood Pressure with Post-discharge Outcomes Using Electronic Medical Record Data: a Retrospective Study

Khambaty

Sahni

2019

J GEN INTERN MED

View full text Add to dashboard Cite

“…Mean ages of participants ranged from 47.1 years [30] to 85 years. [31] Mean percentage of females in study cohorts was 45.0% (SD: 19.2) with four studies excluding females [2,6,32,33] and one study excluding males. [34] Follow-up interval ranged from 12 months [9,35,36] to 20 years.…”

Section: Study Characteristicsmentioning

confidence: 99%

“…[34] Follow-up interval ranged from 12 months [9,35,36] to 20 years. [37] Thirty-nine studies were conducted in a hospital setting, [4,8,10,11,14,15,19,25,31,[33][34][35][36][38][39][40][41][42][43][44][45][46][47][48][49][50][52][53][54][55][56][57][58][59][60][61]64,69,71] whilst 21 studies were conducted in the community. [1-3,,5,6,9,12,13,16,20,21,30,37,51,62,63,65-68,70] -This was not documented in one paper.…”

Section: Study Characteristicsmentioning

confidence: 99%

“…Thirty studies (49%) measured blood pressure over 24 to 26 hours (short-term) using ambulatory BP monitors, [1][2][3][4][5][6][8][9][10][11][12][14][15][16][17]33,[35][36][37]40,42,52,54,57,60,61,63,65,67,69]; in 34 studies (56%), 'day-byday' variability was determined in participants who self-measured blood pressure for 7-28 days with home blood pressure monitors (HBPM) (long-term). [8,13,[19][20][21]25,30,31,[34][35][36]38,39,41,[43][44][45][46][47][48][49]…”

Section: Study Characteristicsmentioning

confidence: 99%

See 1 more Smart Citation

Association between different methods of assessing blood pressure variability and incident cardiovascular disease, cardiovascular mortality and all-cause mortality: a systematic review

et al. 2020

View full text Add to dashboard Cite

Background Blood pressure variability (BPV) is a possible risk factor for adverse cardiovascular outcomes and mortality. There is uncertainty as to whether BPV is related to differences in populations studied, measurement methods or both. We systematically reviewed the evidence for different methods to assess blood pressure variability (BPV) and their association with future cardiovascular events, cardiovascular mortality and all-cause mortality. Methods Literature databases were searched to June 2019. Observational studies were eligible if they measured short-term BPV, defined as variability in blood pressure measurements acquired either over a 24-hour period or several days. Data were extracted on method of BPV and reported association (or not) on future cardiovascular events, cardiovascular mortality and all-cause mortality. Methodological quality was assessed using the CASP observational study tool and data narratively synthesised. Results Sixty-one studies including 3,333,801 individuals were eligible. BPV has been assessed by various methods including ambulatory and home-based BP monitors assessing 24-hour, “day-by-day” and “week-to-week” variability. There was moderate quality evidence of an association between BPV and cardiovascular events (43 studies analysed) or all-cause mortality (26 studies analysed) irrespective of the measurement method in the short- to longer-term. There was moderate quality evidence reporting inconsistent findings on the potential association between cardiovascular mortality, irrespective of methods of BPV assessment (17 studies analysed). Conclusion An association between BPV, cardiovascular mortality and cardiovascular events and/or all-cause mortality were reported by the majority of studies irrespective of method of measurement. Direct comparisons between studies and reporting of pooled effect sizes were not possible.

show abstract

“…Other studies have found a correlation between arterial stiffness and mortality in old patients (usually older than 65 years) [ 12 , 13 ] or in those with heart failure with preserved ejection fraction (mean age 75) [ 14 ]. The prognostic impact of BP variability is also controversial in such populations [ 15 , 16 , 17 , 18 , 19 ].…”

Section: Introductionmentioning

confidence: 99%

Pulse Wave Velocity and Blood Pressure Variability as Prognostic Indicators in Very Elderly Patients

Sierra

Murillo

et al. 2023

JCM

View full text Add to dashboard Cite

There is scarce evidence for the prognostic importance of hemodynamic measures, such as blood pressure (BP), BP variability, and arterial stiffness, in the very elderly population with advanced chronic conditions. We aimed to evaluate the prognostic importance of 24 h BP, BP variability, and arterial stiffness in a cohort of very elderly patients admitted to the hospital due to a decompensated chronic disease. We studied 249 patients older than 80 (66% women; 60% congestive heart failure). Noninvasive 24 h monitoring was used to determine 24 h brachial and central BP, BP and heart rate variabilities, aortic pulse wave velocity, and BP variability ratios during admission. The primary outcome was 1-year mortality. Aortic pulse wave velocity (3.3 times for each SD increase) and BP variability ratio (31% for each SD increase) were associated with 1-year mortality, after adjustments for clinical confounders. Increased systolic BP variability (38% increase for each SD change) and reduced heart rate variability (32% increase for each SD change) also predicted 1-year mortality. In conclusion, increased aortic stiffness and BP and heart rate variabilities predict 1-year mortality in very elderly patients with decompensated chronic conditions. Measurements of such estimates could be useful in the prognostic evaluation of this specific population.

show abstract

High blood pressure variability predicts 30-day mortality but not 1-year mortality in hospitalized elderly patients

Abstract: Day-to-day BPV is associated with 30-day, but not with 1-year mortality in hospitalized elderly patients.

Cited by 3 publications

References 17 publications

Association of Final Discharge Blood Pressure with Post-discharge Outcomes Using Electronic Medical Record Data: a Retrospective Study

Association of Final Discharge Blood Pressure with Post-discharge Outcomes Using Electronic Medical Record Data: a Retrospective Study

Association between different methods of assessing blood pressure variability and incident cardiovascular disease, cardiovascular mortality and all-cause mortality: a systematic review

Pulse Wave Velocity and Blood Pressure Variability as Prognostic Indicators in Very Elderly Patients

Contact Info

Product

Resources

About