High Cell Density Cultivation (HCDC) of E. coli with Intensive Multiple Sequential Batches Together with Fed-Batch at Cell Level (FBC) Superior to the Fed-Batch Technique
Abstract:High cell density cultivation (HCDC) is a technique that was developed and used in the cultivation of various microorganisms. Escherichia coli is the most prominent in the bacterial group and popular at the industrial scale for the production of bio-products. The HCDC conducted with the Fed-Batch modes is complicated. In this study, we developed a batch production medium (BPM), a minimal-defined medium for industrial utilization with the potential use of dextrin at high concentrations as the major carbon sour… Show more
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