High Diabetes Prevalence among Tuberculosis Cases in Kerala, India

Balakrishnan, Shibu; Vijayan, Shibu; Nair, Sanjeev; Subramoniapillai, Jayasankar; Mrithyunjayan, Sunilkumar; Wilson, Nevin; Satyanarayana, Srinath; Dewan, Puneet; Kumar, Ajay M. V.; Karthickeyan, Durai; Willis, Matthew; Harries, Anthony; Nair, Sreenivas Achuthan

doi:10.1371/journal.pone.0046502

Cited by 164 publications

(191 citation statements)

References 15 publications

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“…A study conducted by Shibu Balakrishnan et al about the diabetes prevalence among Tuberculosis cases in Kerala, they got 44% of TB patients are diabetic and this was the highest reported prevalence of DM among TB patients to date. 6 In our study 11.5% and 10.7% of TB suspects got previous history of TB and family history of TB respectively. Presence of other respiratory illness (asthma, COPD.)…”

mentioning

confidence: 47%

“…Another studies conduted in tribal populations in Madhya Pradesh by Rao et al the prevalence of sputum positive Tuberculosis was 1518 per lakh population very high compared to present study. 6 But a study conducted in south India by Chadha et al the prevalence of sputum positive tuberculosis was 152 per positive 0.183% yes no lakh population. It is comparable with the present study.…”

Section: Sputum Positivity Among Tb Suspectsmentioning

confidence: 97%

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Prevalence of TB suspects, sputum positive TB cases and health seeking behaviour of TB suspects in a coastal ward Thiruvananthapuram corporation, Kerala

Mini¹,

Anuja²,

Rajkafoor³

2017

Int J Community Med Public Health

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INTRODUCTIONIndia still remains as a highest TB burden country in the world. According to WHO global Tuberculosis report 2013 India accounts for nearly a quarter of global burden of cases with approximately 2.8 million prevalent cases and 2.2 million incident cases.1 RNTCP is being implemented in our country from 1997 in a phased manner and by 2006 whole country is being covered by RNTCP. The revised national tuberculosis control programme has been quite successful in achieving high case detection and treatment rates in India.Data from isolated centres suggest a reduction of TB prevalence of up to 50% or more with implementation of RNTCP. 2According to the RNTCP programme the most common symptom to clinically suspect pulmonary TB is persistant cough more than 2 weeks. Sputum smear examination of the TB suspects is the back born of RNTCP to diagnose patients with pulmonary TB and in the country there were about 13000 DMCs under the programme. 3 The reliability cheapness and ease of direct microscopic ABSTRACT Background: The present study was conducted to estimate the prevalence of TB suspects and prevalence of sputum positive TB cases and health seeking behaviour of TB suspects in a coastal ward. Methods: The study was done as a cross sectional house to house survey. The study population was initially screened by a case definition and TB suspects were identified and details about their health seeking behaviour was collected using a structured questionnaire and two sputum samples (one spot and one early morning sample) also were collected for sputum microscopy. Results: The population screened using the case definition was 5466 (86% of total population above 15 years of age) and among this 131 (2.39%) was identified as TB suspects. Among the TB suspects 46.6% were males, 19.8% were diabetic, and 60.3% were having coughed more than 4 weeks. Prevalence of sputum positivity among the TB suspects was 13.1% and in the total study population was0.183%. About the health seeking behaviour only 65.65% have consulted a doctor. Among those consulted doctor, 46.5% were males, 93% have consulted an allopathic doctor and 46.52 have completed the prescribed treatment. Conclusions: The prevalence of TB suspects and sputum positive TB cases is high in this coastal ward and health seeking behaviour of Tb suspects is also very poor. This emphasizes the need for further improvement in case detection and IEC activities about Tuberculosis.

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confidence: 47%

Section: Sputum Positivity Among Tb Suspectsmentioning

confidence: 97%

Prevalence of TB suspects, sputum positive TB cases and health seeking behaviour of TB suspects in a coastal ward Thiruvananthapuram corporation, Kerala

Mini¹,

Anuja²,

Rajkafoor³

2017

Int J Community Med Public Health

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“…A study in Kerala State in South India identified high levels of diabetes (~45%) among newly diagnosed TB patients [36]. Nearly half of these patients were not aware of their diabetic status at the time of screening.…”

Section: Contribution Of or To Policy And Practicementioning

confidence: 99%

Operational research within a Global Fund supported tuberculosis project in India: why, how and its contribution towards change in policy and practice

Sagili¹,

Satyanarayana

Chadha³

et al. 2018

Global Health Action

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Background: The Global Fund encourages operational research (OR) in all its grants; however very few reports describe this aspect. In India, Project Axshya was supported by a Global Fund grant to improve the reach and visibility of the government Tuberculosis (TB) services among marginalised and vulnerable communities. OR was incorporated to build research capacity of professionals working with the national TB programme and to generate evidence to inform policies and practices. Objectives: To describe how Project Axshya facilitated building OR capacity within the country, helped in addressing several TB control priority research questions, documented project activities and their outcomes, and influenced policy and practice. Methods: From September 2010 to September 2016, three key OR-related activities were implemented. First, practical output-oriented modular training courses were conducted (n = 3) to build research capacity of personnel involved in the TB programme, co-facilitated by The Union, in collaboration with the national TB programme, WHO country office and CDC, Atlanta. Second, two large-scale Knowledge, Attitude and Practice (KAP) surveys were conducted at baseline and mid-project to assess the changes pertaining to TB knowledge, attitudes and practices among the general population, TB patients and health care providers over the project period. Third, studies were conducted to describe the project’s core activities and outcomes. Results: In the training courses, 44 participant teams were supported to develop research protocols on topics of national priority, resulting in 28 peer-reviewed scientific publications. The KAP surveys and description of project activities resulted in 14 peer-reviewed publications. Of the published papers at least 12 have influenced change in policy or practice. Conclusions: OR within a Global Fund supported TB project has resulted in building OR capacity, facilitating research in areas of national priority and influencing policy and practice. We believe this experience will provide guidance for undertaking OR in Global Fund projects.

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“…Prevalence of diabetes in patients with tuberculosis from different states of India has varied from 11.6% in Punjab to 44% in Kerala [5,6]. Southern Indian states (Kerala 44%, Tamil Nadu 25%, and Pudicherry 29%) have reported higher prevalence of diabetes mellitus in such cases as compared to the Western (Ahmadabad 15%) or North Indian (Punjab 11.6%) states [5][6][7][8].…”

mentioning

confidence: 99%

“…Southern Indian states (Kerala 44%, Tamil Nadu 25%, and Pudicherry 29%) have reported higher prevalence of diabetes mellitus in such cases as compared to the Western (Ahmadabad 15%) or North Indian (Punjab 11.6%) states [5][6][7][8].…”

mentioning

confidence: 99%

Diabetes mellitus and tuberculosis—a double whammy

Madhu

2017

Int J Diabetes Dev Ctries

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High Diabetes Prevalence among Tuberculosis Cases in Kerala, India

Cited by 164 publications

References 15 publications

Prevalence of TB suspects, sputum positive TB cases and health seeking behaviour of TB suspects in a coastal ward Thiruvananthapuram corporation, Kerala

Prevalence of TB suspects, sputum positive TB cases and health seeking behaviour of TB suspects in a coastal ward Thiruvananthapuram corporation, Kerala

Operational research within a Global Fund supported tuberculosis project in India: why, how and its contribution towards change in policy and practice

Diabetes mellitus and tuberculosis—a double whammy

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