High-Dose-Rate Brachytherapy for Small-Sized Peripherally Located Lung Cancer

Abstract

Brachytherapy has a potential to be a method to treat peripheral T1 N0 M0 NSCLC.

Comparison of 60Cobalt and 192Iridium Sources in High Dose Rate Afterloading Brachytherapy

“…Dosimetric and theoretical studies supported clinical equivalence [3,7,11,13,17]. 60 Co and 192 Ir sources of identical shape and construction show practically identical dose distributions despite definite differences in physical characteristics.…”

Photons or Protons: Precision Radiotherapy of Lung Cancer

“…Local control rates for tumors treated with a BED > 100 were 93.5% versus 80.0% for tumors treated with a BED < 100 [12,21]. First steps have been made with percutaneous or transbronchial brachytherapy in small peripheral pulmonary tumors [9,15].…”

Surgery and Chemotherapy for Small Cell Lung Cancer in Stages I–II with or without Radiotherapy

“…The 5-year overall survival after chemoradiotherapy even for LSCLC in stages I and II is approximately 15%, and ~20-30% of patients relapse locally [4,13,14]. Currently, the role of surgery in very early LSCLC is not strictly defined, and only a few series exist that address a bi-or trimodal treatment approach including chemotherapy and/or radiotherapy.…”