Spectroscopic characterization of a Ho:LuVO4 crystal grown by the Czochralski method has been performed, including the absorption and emission spectra. We demonstrate a 2 μm room temperature Ho:LuVO4 laser, resonantly pumped by a 1.94 μm Tm:YAP laser. By use of an output coupler with T=10% transmission, the Ho:LuVO4 laser generated continuous-wave output power of 2.5 W at 2074.18 nm, with a beam quality factor of Mx2=My2=1.3, for a total incident pump power of 19.4 W. The slope efficiency with respect to the pump power was 17.6%, and the optical-to-optical efficiency was 12.9%. Moreover, we obtained a Ho:LuVO4 laser that operated at 2073.77 and 2055.27 nm, by using different output couplers with transmissions of T=15 and 30%.