High‐frequency (20 MHz) high‐intensity focused ultrasound: New ablative method for color‐independent tattoo removal in 1‐3 sessions. An open‐label exploratory study

Serup, Jørgen; Bove, Torsten; Zawada, Tomasz; Jessen, Alexander; Poli, Mattia

doi:10.1111/srt.12885

Cited by 13 publications

(11 citation statements)

References 29 publications

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“…It is noteworthy and clearly an advantage relative to other methods, except carbon dioxide lasers, that only one treatment was needed. The level of pain was significant, and however, a lower pain level was found in other studies of other anatomical sites than the hands having many sensory nerves [ 12 , 15 ].…”

Section: Discussion/conclusionmentioning

confidence: 69%

“…An earlier experiment has, however, shown significant decrease in pain score by self-administering an anesthetic topical (EMLA®, AstraZeneca) on the targeted area prior to treatment. In this case, pain was almost eliminated, while treatment response and post-treatment healing remained within the range observed in the subjects [ 15 ].…”

Section: Case Presentationmentioning

confidence: 95%

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Removal of Common Warts by High-Intensity Focused Ultrasound: An Introductory Observation

Bove¹,

Zawada²,

Jessen³

et al. 2021

Case Rep Dermatol

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Therapies of common warts are cumbersome and not very effective. Recurrences are common. A new 20 MHz high-intensity focused ultrasound (HIFU) method is introduced as a new potential treatment modality. With HIFU, selected targets in the epidermis and dermis can be treated with full control of the depth and position of the ultrasound lesion and the energy applied to the target. The treatment can be monitored directly in real-time via an integrated dermoscope in the ultrasound probe. Two warts were treated with 8–10 shoulder-by-shoulder treatment doses, focal depth 1.3 mm, and 1.2 J/dose. Pretreatment ultrasound B-mode scanning had shown the thickness and depth of the warts. The treated areas developed a dry wound covered by a crust over the next 1–2 days. After 2 weeks the skin was healed, with no wart and no scar. Observation showed no reoccurrence. HIFU has future potential for treatment of common warts and flat warts, and a broad range of skin lesions being logic further candidates for targeted ablative treatment. One single treatment may suffice. It is, therefore, a new modality in dermatology with a large range of indications.

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Section: Discussion/conclusionmentioning

confidence: 69%

Section: Case Presentationmentioning

confidence: 95%

Removal of Common Warts by High-Intensity Focused Ultrasound: An Introductory Observation

Bove¹,

Zawada²,

Jessen³

et al. 2021

Case Rep Dermatol

Self Cite

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show abstract

“…Different combinations of frequency and intensity power are used for different US applications. High-frequency and intensity ultrasound combination is generally used for non-food applications such as soft tissue surgery, diagnostic imaging, or drug delivery [ 27 ]. Similarly, high-frequency and low-intensity US is used in the simulation of tissue regeneration [ 26 ].…”

Section: Ultrasound Technologymentioning

confidence: 99%

Recent innovations of ultrasound green technology in herbal phytochemistry: A review

Gouda

Bekhit

Tang

et al. 2021

Ultrasonics Sonochemistry

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Highlights Ultrasound enhances the phenolic compounds in extracted herbal oils by 44%. US (25–50 kHz) increases the yields of polyphenols, carotenoids, and flavonoids. Radicals generated by US have positive and negative effects on enzymes. US improves the efficiency of herbal extracts in Nanotechnology applications. Acoustic-based biosensors could be used for chemical imaging of herbal tissues.

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“…In case treatment is performed on specially pain-sensitive anatomic locations or sensitive patient groups, use of topical anesthesia (EMLA ® , AstraZeneca) has previously been shown to decrease treatment pain significantly without affecting treatment results. 16 If necessary, topical anesthesia can therefore be prescribed as a standard self-administered pre-treatment option.…”

Section: Discussionmentioning

confidence: 99%

Treatment of Seborrheic Keratosis by High Frequency Focused Ultrasound – An Early Experience with 11 Consecutive Cases

Calik¹,

Migdal²,

Zawada³

et al. 2022

CCID

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Purpose High intensity focused ultrasound operating at 20 MHz has been demonstrated as a safe and efficient treatment modality for a range of dermatological indications. The method is potentially also applicable to removal of seborrheic keratosis. Patients and Methods A total of 54 seborrheic keratoses in 11 volunteer subjects (8 women and 3 men, average age 51.5 ± 13.2 years) were treated in a single session with a medical 20 MHz high intensity focused ultrasound device developed for dermatological conditions. Handpieces with nominal focal depths of 0.8 mm below the skin surface were used to administer acoustic energy of 0.99–1.2 J/dose. An integrated dermoscope in the handpiece was used to monitor the treatment in real-time. Treatment efficacy and side-effects were assessed directly after treatment and at follow-up 4–15 weeks after treatment. Results The treatment showed positive results in 96.3% of the cases. About 68.5% of the cases were classified as complete response and 27.8% of the cases as partial response. Two cases (3.7%) did not respond to treatment and were classified as stable condition. No subjects experienced worsening of their condition, and no treatment received the classification of progressive condition. Side effects were primarily redness in the treatment area due to superficial telangiectasia, mild scarring, and persisting and slow-healing lichen planus-like keratosis. No adverse events were observed. Conclusion HIFU is concluded to be a safe and efficient skin treatment for seborrheic keratoses. It has advantages over conventional treatments that can lead to pain during treatment and scarring after healing.

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High‐frequency (20 MHz) high‐intensity focused ultrasound: New ablative method for color‐independent tattoo removal in 1‐3 sessions. An open‐label exploratory study

Cited by 13 publications

References 29 publications

Removal of Common Warts by High-Intensity Focused Ultrasound: An Introductory Observation

Removal of Common Warts by High-Intensity Focused Ultrasound: An Introductory Observation

Recent innovations of ultrasound green technology in herbal phytochemistry: A review

Treatment of Seborrheic Keratosis by High Frequency Focused Ultrasound – An Early Experience with 11 Consecutive Cases

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