High-frequency oscillatory ventilation in children: a single-center experience of 53 cases

Slee-Wijffels, Fieke Y A M; Vaart, Klara R M van der; Twisk, Jos W. R.; Markhorst, Dick G.; Plötz, Frans B.

doi:10.1186/cc3520

Cited by 33 publications

(9 citation statements)

References 18 publications

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“…As the debate about the value of HFOV in pediatric respiratory failure refractory to conventional means continues, the greater the need to share different experiences from different areas of the world to try to add to our understanding of this unresolved issue. We were able to demonstrate the clear value of HFOV rescue therapy in improving both oxygenation and ventilation as has been described by others from different areas of the world in our study population [1][2][3][4][5]. The majority of our patients had DAD as a pathophysiology, which explained the failure of both oxygenation and ventilation.…”

Section: Discussionsupporting

confidence: 82%

“…By using HFOV, we recruit diseased lung and improve oxygenation, and to some degree ventilation, by constantly distension using high mean airway pressure (MAP) with tidal volume less than anatomic dead space. Several studies in medical literature have suggested more improvement, mainly in oxygenation and also in ventilation, in patients managed with HFOV when compared to conventional mechanical ventilation (CMV) [1][2][3][4][5]. Despite the wide use in all age groups and many success stories with this mode of HFOV, some newly published studies have described contradicting results.…”

Section: Introductionmentioning

confidence: 99%

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High Frequency Oscillatory Ventilation in Pediatric Practice: A Single Center Experience in Saudi Arabia

Gabr¹,

Aboo²,

Zahraa³

2021

Int J Pediatr Neonat Care

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No standardized international practice guidelines are available for the proper indications for switching from conventional mode to HFOV, which cases will improve better on HFOV, and proper adjustment of the HFOV settings. Therefore, the objectives of this study were to identify which patient profiles could be best treated with HFOV in medical centers, especially with the lack of readily available extracorporeal membranous oxygenation (ECMO) rescue therapy, which ones will not improve or even worsen the condition, and the best possible way of selecting and adjusting HFOV settings in the first 48 h. Materials and MethodsA retrospective observational study was conducted in the pediatric intensive care unit (PICU) at King Fahad Medical City (KFMC), a tertiary care hospital located in Riyadh, the capital of Saudi Arabia, between September 2010 and December 2017. All patients under

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Section: Discussionsupporting

confidence: 82%

Section: Introductionmentioning

confidence: 99%

High Frequency Oscillatory Ventilation in Pediatric Practice: A Single Center Experience in Saudi Arabia

Gabr¹,

Aboo²,

Zahraa³

2021

Int J Pediatr Neonat Care

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“…This was observed in 92% of the patients in this case series. In children, an effective CO 2 removal has been demonstrated by HFOV [ 25 ]. Several studies in adults, however, found PaCO 2 increasing or unchanged during HFOV [ 12 , 13 , 26 - 28 ].…”

Section: Discussionmentioning

confidence: 99%

High-frequency oscillation ventilation for hypercapnic failure of conventional ventilation in pulmonary acute respiratory distress syndrome

2015

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IntroductionHigh-frequency oscillation ventilation (HFOV) is regarded as particularly lung protective. Recently, HFOV has been shown to be not beneficial for acute respiratory distress syndrome (ARDS) patients in general. Due to its special physical effects, it could be beneficial, however, in inhomogeneous ARDS. This study evaluates the effect of HFOV on PaCO2 removal in hypercapnic patients with ARDS of pulmonary origin.MethodsBetween October 2010 and June 2014 patients with ARDS of pulmonary origin with PaO2/FiO2 ratio >60 mmHg, but respiratory acidosis (pH <7.26) under optimized protective ventilation were switched to HFOV, using moderate airway pressure (adopting the mean airway pressure of the prior ventilation). Data from these patients were analyzed retrospectively; PaCO2 and pH before, 1 h and 24 h after the start of HFOV were compared.ResultsTwenty-six patients with PaO2/FiO2 ratio 139 ± 49 and respiratory acidosis (PaCO2 68 ± 12 mmHg) were put on HFOV after 17 ± 22 h of conventional ventilation. Mean airway pressure was 19 cm H2O (15 to 28). PaCO2 decreased significantly: after 1 hour the mean difference was −14 ± 10 mmHg; P <0.01 and after 24 hours −17 ± 12 mmHg; P <0.01; n = 24. CO2 clearance improved in all but two patients; in those, extracorporeal lung support was initiated. Oxygenation remained unchanged after 1 h and slightly increased after 24 h. No complications related to HFOV were observed. Twenty-two patients improved and could be weaned from HFOV. Twenty patients (77%) were alive on day 30.ConclusionsHFOV could be a useful alternative in patients with ARDS of pulmonary origin with hypercapnic failure of lung-protective conventional ventilation.Electronic supplementary materialThe online version of this article (doi:10.1186/s13054-015-0935-4) contains supplementary material, which is available to authorized users.

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“…Slee-Wijffels and colleagues [ 7 ], in a retrospective single centre study, reported on the use of HFOV in paediatric patients ( n = 53) who deteriorated on CMV. They observed that HFOV rescue therapy was associated with a high overall survival (64%).…”

Section: Mechanical Ventilationmentioning

confidence: 99%

Year in review 2005: Critical Care - Respirology: mechanical ventilation, infection, monitoring, and education

2006

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We summarize all original research in the field of respiratory intensive care medicine published in 2005 in Critical Care. Twenty-seven articles were grouped into the following categories and subcategories to facilitate rapid overview: mechanical ventilation (physiology, spontaneous breathing during mechanical ventilation, high frequency oscillatory ventilation, side effects of mechanical ventilation, sedation, and prone positioning); infection (pneumonia and sepsis); monitoring (ventilatory monitoring, pulmonary artery catheter and pulse oxymeter); and education (training and health outcome).

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High-frequency oscillatory ventilation in children: a single-center experience of 53 cases

Abstract: Introduction The present article reports our experience with high-frequency oscillatory ventilation (HFOV) in pediatric patients who deteriorated on conventional mechanical ventilation.

Cited by 33 publications

References 18 publications

High Frequency Oscillatory Ventilation in Pediatric Practice: A Single Center Experience in Saudi Arabia

High Frequency Oscillatory Ventilation in Pediatric Practice: A Single Center Experience in Saudi Arabia

High-frequency oscillation ventilation for hypercapnic failure of conventional ventilation in pulmonary acute respiratory distress syndrome

Year in review 2005: Critical Care - Respirology: mechanical ventilation, infection, monitoring, and education

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