High-Frequency Oscillatory Ventilation versus Conventional Mechanical Ventilation for Very-Low-Birth-Weight Infants

Courtney, Sherry E.; Durand, David J.; Asselin, Jeanette M.; Hudak, Mark L.; Aschner, Judy L.; Shoemaker, Craig T

doi:10.1056/nejmoa012750

Cited by 366 publications

(213 citation statements)

References 56 publications

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“…To avoid any interference of mechanical ventilation with these parameters, we stopped the oscillations during HFOV, making extubation a true transition from endotracheal to nasal CPAP. According to our local protocol, infants were extubated to a nasal CDP 2 cmH 2 O lower than during HFOV, because it has been suggested that the alveolar CDP delivered by the SensorMedics 3100 ventilator is 1-2 cmH 2 O lower than the pressure recorded at the hub of the endotracheal tube when delivered with an inspiratory time of 33%, as is custom in our unit (18)(19)(20). Despite this lower CDP EELV remained stable after extubation.…”

Section: Discussionmentioning

confidence: 99%

Changes in lung volume and ventilation following transition from invasive to noninvasive respiratory support and prone positioning in preterm infants

et al. 2014

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Section: Discussionmentioning

confidence: 99%

Changes in lung volume and ventilation following transition from invasive to noninvasive respiratory support and prone positioning in preterm infants

et al. 2014

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“…Two recent studies, published in the same journal and using similar methodologies, found differing results. 36 Courtney et al 37 compared HFOV with SIMV in infants of 600 to 1200 g birthweight and found a small reduction in the incidence of CLD. However, it is plausible that this difference might be more attributable to the use of SIMV in the control group, and that if A/C had been used, it might have even disappeared.…”

Section: Clinical Evidencementioning

confidence: 99%

Neonatal ventilators: how do they differ?

Donn

2009

J Perinatol

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Remarkable technological advances over the past two decades have brought dramatic changes to the neonatal intensive care unit. Microprocessor-based mechanical ventilation has replaced time-cycled, pressure-limited, intermittent mandatory ventilation with almost limitless options for the management of respiratory failure in the prematurely born infant. Unfortunately, much of the infusion of technology occurred before the establishment of a convincing evidence base. This review focuses on the basic principles of mechanical ventilation, nomenclature and the characteristics of both conventional and high-frequency devices.

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“…Porém, nas últimas 2 décadas, vários estudos clínicos têm sido realizados, e os resultados continuam controversos [57][58][59][60][61][62][63][64][65] . Duas revisões feitas pela Cochrane Database não evidenciaram grandes vantagens do uso da ventilação de alta freqüência.…”

Section: Ventilação De Alta Freqüênciaunclassified

Strategies to minimize lung injury in extremely low birth weight infants

Suguihara¹,

Lessa²

2005

J Pediatr (Rio J)

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Como citar este artigo: Suguihara C, Lessa AC. Como minimizar a lesão pulmonar no prematuro extremo: propostas. J Pediatr (Rio J). 2005;81(1 Supl):S69-S78. AbstractObjective: To review the main causes of new bronchopulmonary dysplasia and the strategies utilized to decrease its incidence in extremely low birth weight infants. Sources of data:For this review a MEDLINE search from 1966 to October 2004, the Cochrane Database, abstracts from the Society for Pediatric Research and recent meetings on the topic were used. Summary of the findings:The survival of extremely low birth weight infants has increased significantly due to improvement in both scientific knowledge and technology. This improvement in survival has therefore resulted in an increased incidence of bronchopulmonary dysplasia. The characteristics of bronchopulmonary dysplasia in extremely low birth weight infants, the so called new bronchopulmonary dysplasia are quite different from the classic bronchopulmonary dysplasia described by Northway. This new bronchopulmonary dysplasia has a multifactorial etiology, which includes volutrauma, atelectrauma, oxygen toxicity and lung inflammation. Therapy such as prenatal corticosteroids, exogenous surfactant, nasal continuous positive airway pressure, new mechanical ventilation modalities and gentle ventilation have been used in attempts to decrease lung injury severity. Conclusions:In order to prevent lung injury in extremely low birth weight infants, it is necessary to minimize several factors that induce bronchopulmonary dysplasia and to utilize less aggressive therapeutic strategies. In addition to the current therapy used to decrease lung injury, knowledge of these causative factors may create new therapies that may be fundamental in improving the clinical outcomes of premature infants.J Pediatr (Rio J). 2005;81(1 Supl):S69-S78: Extremely low birth weight infant, bronchopulmonary dysplasia, mechanical ventilation. ResumoObjetivo: Apresentar uma revisão das principais causas da nova displasia broncopulmonar e as estratégias utilizadas para diminuir sua incidência nos prematuros extremos. Fontes dos dados:Para essa revisão, pesquisas foram feitas na MEDLINE (1996 a outubro de 2004), no Cochrane Database, em resumos da Society for Pediatric Research e recentes conferências sobre o tema. Síntese dos dados:A tecnologia e os novos conhecimentos científicos têm aumentado significantemente a sobrevida de prematuros extremos. Esse aumento da sobrevida resultou em aumento da incidência de displasia broncopulmonar. Atualmente, a displasia broncopulmonar é mais freqüentemente observada em recém-nascidos < 1.200 g. As características da displasia broncopulmonar nesses prematuros extremos, atualmente chamada de nova displasia broncopulmonar, são bastante diferentes da clássica descrita por Northway. A nova displasia broncopulmonar tem etiologia multifatorial, como volutrauma, atelectrauma, toxicidade ao oxigênio e reação inflamatória. Terapias como corticosteróide pré-natal, surfactante exógeno, pressão aérea positiva co...

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High-Frequency Oscillatory Ventilation versus Conventional Mechanical Ventilation for Very-Low-Birth-Weight Infants

Abstract: There was a small but significant benefit of high-frequency oscillatory ventilation in terms of the pulmonary outcome for very-low-birth-weight infants without an increase in the occurrence of other complications of premature birth.

Cited by 366 publications

References 56 publications

Changes in lung volume and ventilation following transition from invasive to noninvasive respiratory support and prone positioning in preterm infants

Changes in lung volume and ventilation following transition from invasive to noninvasive respiratory support and prone positioning in preterm infants

Neonatal ventilators: how do they differ?

Strategies to minimize lung injury in extremely low birth weight infants

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