High‐grade osteosarcoma treated with hemicortical resection and biological reconstruction

Abstract

Hemicortical resection for high-grade osteosarcomas located eccentrically in the long bones may be a reliable technique leading to good joint function by preserving surrounding healthy tissues. The functional outcome was encouraging, although long-term follow-up is mandatory to validate. With the advancement of chemotherapy and radiographic three-dimensional imaging, the safe margin in wide excision of high-grade osteosarcoma may be narrowed down in light of joint surface preservation.

Hemicortical Resection and Inlay Allograft Reconstruction for Primary Bone Tumors

“…Other authors reported no fractures, but they did not describe the extent of cortical resection, which was the most important risk factor in our patients [12][13][14]24 . The association between fractures and the extent of cortical resection may be explained by greater stresses acting on a smaller portion of remaining cortex 25 .…”

“…It may result in lower complication rates and allow faster and more complete rehabilitation 3,11,12 . Various reconstructive techniques have been described, including implantation of cortical allografts, autografts, and autologous iliac crest grafts 3,[11][12][13][14][15] . Allografts have been most commonly used, but there is a lack of studies of large series with such reconstructions.…”

“…More recently, authors have described experiences with limited resection of high-grade lesions 13,16 . The authors of most studies on hemicortical resection of bone tumors reported that no recurrences occurred 3,11-15 .…”

Knee joint preservation surgery in osteosarcoma using tumour-bearing bone treated with liquid nitrogen

“…The purpose of a wide surgical margin is to reduce the risk of local recurrence. However, additional resection of normal tissue can jeopardize vital structures, including ligaments, tendons, and physes, and can possibly lead to restricted limb function and limb length discrepancy [3]. The traditional 2-3-cm-wide margin has recently been questioned, and methods using a reduced margin and partial epiphyseal preservation to improve host tissue preservation have been reported [3][4][5][6].…”

RECONSTRUCTION OF BONE DEFECTS AFTER TUMOR RESECTION BY AUTOAND ALLOGRAFTS (review of literature)

“…К аналогичным выводам приш-ли и другие авторы [33,[39][40][41][42][43][44][45][46][47][48]. по данным лите-ратуры, 5-летняя выживаемость пациентов сос-тавляет 73% и выше, рецидивирование опухоли возникает менее чем в 13%, при этом авторы не связывают эти случаи с применением аллотранс-плантата [39,43,48].…”