High-intensity aerobic interval training and resistance training are feasible in rectal cancer patients undergoing chemoradiotherapy: a feasibility randomized controlled study

Piraux, Elise; Reychler, Grégory; Vancraeynest, David; Geets, Xavier; Diller, Leonard; Caty, Gilles

doi:10.5603/rpor.a2022.0036

Cited by 14 publications

(60 citation statements)

References 43 publications

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“…Langlais et al 30 . reported a positive change while the other two studies, 31,45 conducted by the same author, showed opposite effects. However, it is important to note that CGs presented higher sleep quality decreases compared to RT groups.…”

Section: Discussionmentioning

confidence: 95%

“…Out of 21 RCTs, 19 (90.5%) included patients on treatment, 29–33,36–49 while 2 (9.5%) studies included patients off treatment 34,35 . Studies recruited individuals with breast ( N = 8), 32–37,41,46 prostate ( N = 5), 29–31,41,46 colorectum ( N = 4), 39,41,43,45 liquid cancer species ( N = 4), 38,40,42,44 pancreatic ( N = 2), 43,47 and esophageal ( N = 1) cancer 48 . One of these studies included gastrointestinal cancer patients, also recruiting gastric and biliary tract cancer patients 43 .…”

Section: Resultsmentioning

confidence: 99%

“…Training modalities performed by the intervention groups in the selected studies consisted of RT alone ( N = 8; 38.1%), 30,31,36,37,42,43,45,47 or a combination of RT and AT ( N = 13; 61.9%) 29,32–35,38–41,44,46,48,49 . RT interventions mostly consisted of machine‐based exercises ( N = 13) 29–37,41,43,45,47 . Seven studies applied free weight strategies, 30,31,35,44,45,48,49 and six studies implemented RT through the use of resistance bands 38–40,42,46,47 .…”

Section: Resultsmentioning

confidence: 99%

“…47 The median duration of the interventions was 12 [8,17] weeks, with the majority of the studies with a duration ≥12 weeks (N = 15; 71%) 29,30,[32][33][34][35][36][37]40,41,43,44,[47][48][49] and with 6 studies (29%) with an intervention shorter than 12 weeks. 31,38,39,42,45,46 The median frequency of the interventions was 3 [2,3] times a week, with 9 (43%) studies reporting a frequency of 3 times a week, [30][31][32][33][34][35]42,45,49 and 7 (33.3%) studies reporting a 2 times a week frequency. 29,36,37,43,44,47,48 Four more studies presented more than four trainings a week (19%) 38,39,41,46 and one did not report this information (4.7%).…”

Section: Study Characteristicsmentioning

confidence: 99%

“…[38][39][40]42,46,47 Two of the abovementioned studies also delivered bodyweight training. 31,45 The majority of the studies had supervised components, with 13 29,31,32,[34][35][36][37][38][43][44][45]47,48 implementing a fully supervised approach and four administering mixed approaches (supervised and home-based together). 33,41,42,49 The remaining five studies delivered home-based interventions.…”

Section: Study Characteristicsmentioning

confidence: 99%

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Effects of resistance training on sleep quality and disorders among individuals diagnosed with cancer: A systematic review and meta‐analysis of randomized controlled trials

Maric,

Ficarra,

Di Bartolo

et al. 2024

Cancer Medicine

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BackgroundSleep disorders are often complained by cancer patients and can last years after the end of therapies, leading to different negative consequences. Non‐pharmacological strategies such as exercise interventions may be considered to counteract this phenomenon. The literature supports the beneficial effects of aerobic training (AT), while evidence on resistance training (RT) is scarce. Accordingly, our systematic review aims to investigate the potential novel effect of RT on sleep outcomes in cancer survivors.MethodsThe literature search was conducted on MEDLINE (Pubmed), Web of Science, Scopus, and Cochrane Central Register of Controlled Trials databases, including only randomized controlled trials (RCTs). The screening procedure was conducted using the web‐based software COVIDENCE. Sleep outcomes assessed through self‐reported questionnaires or objective sleep measurements were extracted from RCTs recruiting cancer survivors of any age and gender, on or off treatment. The risk of bias (RoB) for each study was assessed using the Cochrane RoB 2 tool for RCTs. Meta‐analytic syntheses were performed on sleep quality and insomnia.ResultsA total of 21 studies were included in the review. Considering the mean percentage differences of all studies combined, promising positive results were found after combined aerobic and resistance exercise program (COMB) for sleep quality (−19%) and sleep disturbance (−17.3%). The meta‐analysis results showed significant improvement for both sleep quality and insomnia (d = 0.28, SE: 0.11, Z = 2.51, p < 0.01, 95% CI: 0.07–0.49 and d = 0.43, SE: 0.20, Z = 2.18, p = 0.029, 95% CI: 0.07–0.49, respectively).ConclusionRT interventions of 60 minutes per session, performed 2–3 times a week for 12 weeks, with exercise intensity ranging from 60% to 80% of one‐repetition maximum can be administered to cancer survivors, aiming to improve sleep outcomes.

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Section: Discussionmentioning

confidence: 95%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Study Characteristicsmentioning

confidence: 99%

Section: Study Characteristicsmentioning

confidence: 99%

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Effects of resistance training on sleep quality and disorders among individuals diagnosed with cancer: A systematic review and meta‐analysis of randomized controlled trials

Maric,

Ficarra,

Di Bartolo

et al. 2024

Cancer Medicine

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Aerobic Physical Activity and Depression Among Patients With Cancer

Kulchycki,

Halder,

Askin

et al. 2024

JAMA Netw Open

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ImportanceDepression is prevalent among patients with cancer, affecting their quality of life and survival. Aerobic physical activity (APA) is an effective strategy for managing depression in the general population, but its effectiveness for reducing depressive symptoms among patients with cancer requires further study.ObjectiveTo evaluate whether APA decreases depression severity in patients with cancer by synthesizing data from published randomized clinical trials (RCTs).Data SourcesSix databases (MEDLINE, Embase, Cochrane Central Register of Controlled Trials, CINAHL, PsycINFO, and Scopus) were systematically searched for relevant citations published between January 1, 1980, and July 5, 2023.Study SelectionThis systematic review and meta-analysis included RCTs comparing APA interventions with usual care, waitlist control, or attention control for managing depression in patients with cancer, irrespective of age and cancer type.Data Extraction and SynthesisTwo reviewers independently conducted screening and data extraction. Risk of bias was evaluated using the Cochrane Risk of Bias Tool, version 2. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) reporting guideline was followed. Standardized mean differences (SMDs) were calculated using a random-effects model. Data collection and analyses were performed between June 2022 and March 2024.Main Outcomes and MeasuresThe primary outcome was severity of self-reported depression reported within 1 month of the end of intervention (short term). Secondary outcomes were severity of self-reported depression between 1 and 6 months post intervention (medium term) and between 6 and 12 months post intervention (long term).ResultsThis meta-analysis included 25 RCTs with a total of 1931 adults with cancer (age range, 18-80 years). Ten RCTs (40%) had low risk of bias. Aerobic physical activity was associated with decreased self-reported depression among adults with cancer across the 25 included trials (n = 1931 participants; SMD, −0.38 [95% CI, −0.59 to −0.18]; P &lt; .001; I2 = 76%). This decrease in depression scores was also significant for the secondary outcomes of long-term depression across 3 trials (n = 299 participants; SMD, −0.32 [95% CI, −0.60 to −0.04]; P = .03; I2 = 31%) but not for medium-term depression across 2 trials (n = 143 participants; SMD, −0.27 [95% CI, −0.60 to 0.06]; P = .10; I2 = 0%).Conclusions and RelevanceIn this systematic review and meta-analysis, APA was associated with modest short-term and long-term reductions of depression among adults with cancer. Future studies should discern the effectiveness of APA in combination with other strategies for managing depression across various populations of patients with cancer.

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Effects of high-intensity interval training on functional performance and maximal oxygen uptake in comparison with moderate intensity continuous training in cancer patients: a systematic review and meta-analysis

Neuendorf,

Haase,

Schroeder

et al. 2023

Support Care Cancer

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Introduction High-intensity interval training (HIIT) is an appropriate training modality to improve endurance and therefore contributes to physical performance. This review investigates the effect of HIIT on functional performance in cancer patients. We reviewed the relative peak oxygen uptake (relV̇O2PEAK) and meta-analytical compared HIIT with moderate intensity continuous training (MICT). Furthermore, we took various training parameters under consideration. Methods A systematic literature search was conducted in Scopus, PubMed, and Cochrane Library databases. For the review, we included randomized controlled trials containing HIIT with cancer patients. From this, we filtered interventions with additional MICT for the meta-analysis. Outcomes of interest were various functional performance assessments and V̇O2MAX. Results The research yielded 584 records which fit the inclusion criteria, of which 31 studies with n=1555 patients (57.4±8.6 years) could be included in the overall review and 8 studies in the meta-analysis (n=268, 59.11±5.11 years) regarding relV̇O2PEAK. Different functional outcomes were found, of which walking distance (+8.63±6.91% meters in 6-min walk test) and mobility (+2.7cm in sit and reach test) improved significantly due to HIIT. In terms of relV̇O2PEAK, the performance of cancer patients was improved by HIIT (10.68±6.48%) and MICT (7.4±4.29%). HIIT can be favored to increase relV̇O2PEAK (SMD 0.37; 95% CI 0.09–0.65; I2=0%; p=0.009). Effect sizes for relV̇O2PEAK improvements correlate moderately with total training volume (Spearman’s ρ=0.49; p=0.03), whereas percentage increases do not (Spearman’s ρ=0.24; p=0.14). Conclusion Functional and physical outcomes were positively altered by different HIIT protocols and forms of implementation, whereas a tendency toward more effectiveness of HIIT vs. MICT was found for relV̇O2PEAK. Future studies should include functional parameters more often, to finally allow a comparison between both training protocols in this regard.

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High-intensity aerobic interval training and resistance training are feasible in rectal cancer patients undergoing chemoradiotherapy: a feasibility randomized controlled study

Cited by 14 publications

References 43 publications

Effects of resistance training on sleep quality and disorders among individuals diagnosed with cancer: A systematic review and meta‐analysis of randomized controlled trials

Effects of resistance training on sleep quality and disorders among individuals diagnosed with cancer: A systematic review and meta‐analysis of randomized controlled trials

Aerobic Physical Activity and Depression Among Patients With Cancer

Effects of high-intensity interval training on functional performance and maximal oxygen uptake in comparison with moderate intensity continuous training in cancer patients: a systematic review and meta-analysis

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