High-performance liquid chromatographic and spectrofluorometric determination of α-tocopherol in a natural plant: Ferula hermonis (Zalooh root)

Aoun, Emile; Rima, Jamil; Chidiac, Ghiwa; Hanna, Khalil

doi:10.1016/j.jfca.2004.06.005

Cited by 10 publications

(7 citation statements)

References 16 publications

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“…Various detectors are equipped with RP-HPLC including UVevis (Zhou et al, 2004), photodiode array (PDA) , fluorescence (Aoun, Rima, Chidiac, & Hanna, 2005) and mass spectrometer (MS) (Tian et al, 2005). Since phenolic compounds possess antioxidant activities, it is worthwhile to investigate their antioxidant activities along with their quantities.…”

Section: Introductionmentioning

confidence: 99%

High performance liquid chromatographic analysis of phenolic compounds and their antioxidant activities in rice varieties

Vichapong

Sookserm

Srijesdaruk

et al. 2010

LWT - Food Science and Technology

131

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Section: Introductionmentioning

confidence: 99%

High performance liquid chromatographic analysis of phenolic compounds and their antioxidant activities in rice varieties

Vichapong

Sookserm

Srijesdaruk

et al. 2010

LWT - Food Science and Technology

131

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“…hermonis has attracted a lot of interest not only in view of its aphrodisiac benefits, but also its relatively large amounts of vitamin E content. In this regard, the presence of α-tocopherol in the plant was firstly confirmed by Aoun E. et al in 2004 [58] with HPLC-UV and HPLC-Fl. The mean content of α-tocopherol in F. hermonis was 5 ± 0.5 mg/g.…”

Section: Other Compoundsmentioning

confidence: 76%

Phytochemistry and Pharmacology of Ferula hermonis Boiss. – A Review

Sattar

Iranshahi

2017

Drug Res (Stuttg)

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Ferula hermonis, a well-known species of the genus Ferula found in Lebanon and Syria, has a brilliant history in traditional medicine as it has been used for the treatment of erectile dysfunction in men and menopausal disturbances in women. Thanks to modern pharmacological and clinical investigations, is a valuable medicinal and condimental plant that may be used for the treatment of impotence and diabetes, the prevention of osteoporosis, and possesses anti-microbial and anti-inflammatory properties. Phytochemical investigations have shown that this plant contains daucane aryl esters such as ferutinin, which has exhibited various biological activities including hypoglycemic and estrogenic activities. Ferutinin is one of the strongest natural phytoestrogen which has agonistic activity on estrogen receptors, particularly α receptor. It seems that ferutinin and its derivatives play an important role in biological activities, mainly the beneficial effects of this plant on impotence, diabetes and osteoporosis. The present review discusses the available data on the active constituents and biological activities of and their possible underlying mechanisms of action.

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“…In literature, there are several different methods (18,20,27,28) reported for the quantitaive determination of α-tocopherol in different samples such as natural plants (23), pharmaceutical preparations (24) and human plasma (20,21). Spectrophotometric and chromatografic (liquid, gas, high performance liquid chromatography etc.)…”

Section: Discussionmentioning

confidence: 99%

“…For the determination of α-tocopherol, several methods have been reported in different samples such as foods (18), cosmetics (19), biological fluids (20)(21)(22), natural compounds (23) and pharmaceutical preparations (24) in the literature. Chromatographic methods such as gas chromatography, liquid chromatography and spectroscophic methods such as mass spectrometry, UV-Vis spectrophotometry, flourescence spectrophotometry have been widely used for the quantification of tocopherols (25).…”

Section: Introductionmentioning

confidence: 99%

Farmasötik Yumuşak Kapsülde α-Tokoferolün Spektrofotometri ile Kantitatif Tayini

Artuç¹

2020

Experimed

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Objective: Vitamin E is an essential micronutrient for maintaining a healthy status and preventing disease. The purpose of this study was to develop and validate a simple, sensitive and easily applicable spectrophotometric method for determination of α-tocopherol in pharmaceutical preparations. Material and Method: The quantitative determination of the α-tocopherol in pharmaceutical prepation was carried out using the maximum absorbance value measured at 290 nm. Calibration graphs were constructed by plotting the absorbance against the corresponding concentration of standart α-tocopherol samples at five different concentrations (10-100 µg/mL). Results: The amount of α-tocopherol in the pharmaceutical soft capsule was calculated as 101.572% (203.145 IU/capsule) (Evicap soft capsule labelled content: 200 IU/capsule). Conclusion: It suggested that the developed spectrophotometric method in this study is accurate, sensitive, precise, reproducible and easily applied to soft capsules and the other pharmaceutical preparations.

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High-performance liquid chromatographic and spectrofluorometric determination of α-tocopherol in a natural plant: Ferula hermonis (Zalooh root)

Cited by 10 publications

References 16 publications

High performance liquid chromatographic analysis of phenolic compounds and their antioxidant activities in rice varieties

High performance liquid chromatographic analysis of phenolic compounds and their antioxidant activities in rice varieties

Phytochemistry and Pharmacology of Ferula hermonis Boiss. – A Review

Farmasötik Yumuşak Kapsülde α-Tokoferolün Spektrofotometri ile Kantitatif Tayini

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