High preoperative monocyte count/high-density lipoprotein ratio is associated with postoperative atrial fibrillation and mortality in coronary artery bypass grafting

Abstract

We have observed that high preoperative monocyte count/ high-density lipoprotein ratio was associated with postoperative atrial fibrillation and mortality after coronary artery bypass grafting operation.

<p>The Predictive Value of Monocyte Count to High-Density Lipoprotein Cholesterol Ratio in Restenosis After Drug-Eluting Stent Implantation</p>

“…The rate of NSTE myocardial infarction (NSTEMI) was higher in the ISR group than in the non-ISR group (50.0% vs 16.8%, p=0.001). The rate of presence of a bifurcation lesion was higher and time between the two CAG scans was longer in the ISR group than in the non-ISR group (37.5% vs 15.3%, p=0.019; 27.5 [16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31] vs 23.0, [16][17][18][19][20][21][22][23][24][25][32][33][34][35] p=0.043, respectively). Angiographic and PCI results, including the rate of calcification lesion, lesion type according to the AHA classification, generation of the implanted stents, the total stent length, maximum stent diameter, and post-dilatation indication, were similar in both groups.…”

“…23 Saskin et al reported that high preoperative MHR was associated with postoperative atrial fibrillation and mortality in coronary artery bypass grafting. 24 The relation of MHR with short-and long-term clinical outcome after primary PCI in ST-segment elevation myocardial infarction (STEMI) patients and atrial fibrillation recurrence after ablation procedures is also revealed. [25][26][27] All aforementioned studies showed the clinical value of MHR as a novel inflammation-based prognostic marker in cardiovascular diseases.…”

“…This could partially explain the predictive value of MHR in restenosis after DES implantation. 23,24 Stent fracture is another important mechanism of ISR in DES implantation which distorts the integrity of the stent structure. The incidence rate of stent fracture is higher in the first generation stents than second-generation stents with 0.7% to 18.6% depending on the nature of the studies and the image modality 39. Intravascular imaging technique is useful in recognization stent fracture in ISR patients.…”

Monocyte to high-density lipoprotein cholesterol ratio as long-term prognostic marker in patients with coronary artery disease undergoing percutaneous coronary intervention

“…There is a relationship between the elevation of MHR and presence and severity of isolated coronary artery ectasia [19], asymptomatic organ damage in patients with primary hypertension [20], slow coronary flow [21], cardiac syndrome X [22], metabolic syndrome [23], infective endocarditi [24] and saphenous vein graft disease in coronary bypass [25]. It also has been reported to be related to cardiovascular outcomes in patients with chronic kidney disease [26], arterial fibrillation recurrence after cryoballoon based catheter ablation [27], mortality and arterial fibrillation recurrence after coronary artery bypass grafting [28], and contrast induced nephropathy in acute ST-segment elevation myocardial infarction (STEMI) patients treated with primary PCI [29]. Moreover, there are some researches about the recent evidence suggested that in patients with STEMI, the admission MHR values were independently correlated with poor prognosis as major adverse cardiovascular events and mortality [30–32].…”

Prognostic Value of Inflammation Parameters in Patients With Non-ST Elevation Acute Coronary Syndromes

“…19 Saskin et al claimed that preoperative MHR values were associated with postoperative atrial fibrillation and mortality. 20 In the formation of atherosclerotic plaque, activated circulating monocytes interact with the damaged endothelium and are taken into the intima and turned into macrophages. Macrophages form foam cells by taking LDL and other lipids oxidized with phagocytosis.…”