High‐quality large‐scale longitudinal studies with detailed multimodal immunological phenotyping are warranted to disentangle the involvement of the immune system in psychosis

An international research agenda for clozapine-resistant schizophrenia

“…41 T-cell-mediated inflammatory processes should also be examined in clozapine-resistant schizophrenia. Future multimodal, high-quality, large-scale studies might show whether immunological or inflammatory signatures occur consistently in subgroups of treatment-resistant or clozapine-resistant schizophrenia 43 and whether any of these patients can be diagnosed with an autoimmune psychosis subtype. 40…”