“…In continuation of a previous study dealing with the development of a precise NMR quantitative method for the identification of deuterated organic compounds, 37 Sergeyev et al 38 performed very accurate measurements of chemical shifts and J H,D spin–spin coupling constants of ethanol, propanol, 1,2‐dichloroethane, and 1,4‐dioxane, including those between magnetically equivalent protons (which are not observed in the 1 H NMR spectra). New and/or refined data on the coupling constants retrieved from the studied 2 H NMR spectra of title compounds are exemplified here for ethanol and propanol (see Figures 7 and 8), while measured in the 2 H NMR spectra of those two compounds 2 J H,D and 3 J H,D are compiled in Table 2.…”
Section: Recent Advances and Perspectivesmentioning
confidence: 99%
“… 2 H nuclear magnetic resonance (NMR) spectrum of propanol at 46.05 MHz recorded at 339 K at the natural abundance of deuterium. Reproduced with minor editing privilege from Sergeyev et al 38 with the permission of Springer.…”
Section: Recent Advances and Perspectivesmentioning
confidence: 99%
“…Source: Compiled from Sergeyev et al 38 F I G U R E 9 2 H nuclear magnetic resonance (NMR) 2D doublequantum spectrum of 1-pentanol-d 12 obtained with τ = 1.45 ms; 64 free induction decays were added for each t 1 increment. The five slices parallel to the F 2 axis illustrate the five double-quantum transitions observed in the F 1 axis.…”
Section: Organic Compounds Of Biological Interestmentioning
confidence: 99%
“…I G U R E 7 2 H nuclear magnetic resonance (NMR) spectrum of ethanol at 46.05 MHz recorded at 339 K at the natural abundance of deuterium. Reproduced with minor editing privilege from Sergeyev et al38 with the permission of Springer.F I G U R E 8 2 H nuclear magnetic resonance (NMR) spectrum of propanol at 46.05 MHz recorded at 339 K at the natural abundance of deuterium. Reproduced with minor editing privilege from Sergeyev et al38 with the permission of Springer.T A B L E 2 Proton-deuterium spin-spin coupling constants of the isotopomers of ethanol-d 1 and n-propanol-d 1 , Hz.…”
Present review is focused on recent experimental and computational advances of the liquid-phase deuterium nuclear magnetic resonance (NMR). Nowadays, isotropic liquid-phase 2 H NMR became one of the most important instruments for the identification and certification of organic compounds of biological interest together with natural products and biosynthetic molecules. Of special interest are the 2 H NMR biochemical and microbiological applications. This review consists of three main parts. The first part deals with the practical applications of 2 H NMR to organic compounds of biological interest. The second part is connected with natural products and biosynthetic molecules, while the third part exemplifies and outlines 2 H NMR advances in biochemistry and microbiology.
“…In continuation of a previous study dealing with the development of a precise NMR quantitative method for the identification of deuterated organic compounds, 37 Sergeyev et al 38 performed very accurate measurements of chemical shifts and J H,D spin–spin coupling constants of ethanol, propanol, 1,2‐dichloroethane, and 1,4‐dioxane, including those between magnetically equivalent protons (which are not observed in the 1 H NMR spectra). New and/or refined data on the coupling constants retrieved from the studied 2 H NMR spectra of title compounds are exemplified here for ethanol and propanol (see Figures 7 and 8), while measured in the 2 H NMR spectra of those two compounds 2 J H,D and 3 J H,D are compiled in Table 2.…”
Section: Recent Advances and Perspectivesmentioning
confidence: 99%
“… 2 H nuclear magnetic resonance (NMR) spectrum of propanol at 46.05 MHz recorded at 339 K at the natural abundance of deuterium. Reproduced with minor editing privilege from Sergeyev et al 38 with the permission of Springer.…”
Section: Recent Advances and Perspectivesmentioning
confidence: 99%
“…Source: Compiled from Sergeyev et al 38 F I G U R E 9 2 H nuclear magnetic resonance (NMR) 2D doublequantum spectrum of 1-pentanol-d 12 obtained with τ = 1.45 ms; 64 free induction decays were added for each t 1 increment. The five slices parallel to the F 2 axis illustrate the five double-quantum transitions observed in the F 1 axis.…”
Section: Organic Compounds Of Biological Interestmentioning
confidence: 99%
“…I G U R E 7 2 H nuclear magnetic resonance (NMR) spectrum of ethanol at 46.05 MHz recorded at 339 K at the natural abundance of deuterium. Reproduced with minor editing privilege from Sergeyev et al38 with the permission of Springer.F I G U R E 8 2 H nuclear magnetic resonance (NMR) spectrum of propanol at 46.05 MHz recorded at 339 K at the natural abundance of deuterium. Reproduced with minor editing privilege from Sergeyev et al38 with the permission of Springer.T A B L E 2 Proton-deuterium spin-spin coupling constants of the isotopomers of ethanol-d 1 and n-propanol-d 1 , Hz.…”
Present review is focused on recent experimental and computational advances of the liquid-phase deuterium nuclear magnetic resonance (NMR). Nowadays, isotropic liquid-phase 2 H NMR became one of the most important instruments for the identification and certification of organic compounds of biological interest together with natural products and biosynthetic molecules. Of special interest are the 2 H NMR biochemical and microbiological applications. This review consists of three main parts. The first part deals with the practical applications of 2 H NMR to organic compounds of biological interest. The second part is connected with natural products and biosynthetic molecules, while the third part exemplifies and outlines 2 H NMR advances in biochemistry and microbiology.
The review gathers the most important works on SSCC, considering their practical and theoretical aspects. These chapters deal with the improvement of calculation methods, benchmark calculations using large sets of compounds, measurements of coupling constants in individual compounds, and application of coupling to the exploration of the conformations as well as couplings through unusual chemical bonds. Finally, examples of natural compounds were provided in which J(H,H) and J(C,H) were helpful in determining their structure. This review covers the period from May 2023 to April 2024.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
