High Resolution Biological Visualization Techniques

Pike, Pavlina; Parigger, Christian G.; Splinter, Robert

doi:10.5772/12943

Laser Pulse Phenomena and Applications 2010

DOI: 10.5772/12943

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High Resolution Biological Visualization Techniques

Pavlina Pike¹,

Christian G. Parigger²,

Robert Splinter³

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Cited by 2 publications

References 65 publications

(77 reference statements)

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Optical diagnostic and therapy applications of femtosecond laser radiation using lens-axicon focusing

Parigger

Johnson

Splinter

2013

2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

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Diagnostic modalities by means of optical and/or near infrared femtosecond radiation through biological media can in principle be adapted to therapeutic applications. Of specific interest are soft tissue diagnostics and subsequent therapy through hard tissue such as bone. Femto-second laser pulses are delivered to hydroxyapatite representing bone, and photo-acoustic spectroscopy is presented in order to identify the location of optical anomalies in an otherwise homogeneous medium. Imaging through bone is being considered for diagnostic, and potentially therapeutic, applications related to brain tumors. The use of mesomeric optics such as lens-axicon combinations is of interest to achieve the favorable distribution of focused radiation. Direct therapy by increasing local temperature to induce hyperthermia is one mode of brain tumor therapy. This can be enhanced by seeding the tumor with nanoparticles. Opto-acoustic imaging using femtosecond laser radiation is a further opportunity for diagnosis.

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Optical diagnostic and therapy applications of femtosecond laser radiation using lens-axicon focusing

Parigger

Johnson

Splinter

2013

2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

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show abstract

Physiological sensing through tissue with femto-second laser radiation

Parigger

Johnson

Splinter

2012

High Capacity Optical Networks and Emerging/Enabling Technologies

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High Resolution Biological Visualization Techniques

Cited by 2 publications

References 65 publications

Optical diagnostic and therapy applications of femtosecond laser radiation using lens-axicon focusing

Optical diagnostic and therapy applications of femtosecond laser radiation using lens-axicon focusing

Physiological sensing through tissue with femto-second laser radiation

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