High resolution GC/MS analysis of the Holoptelea integrifoli's leaves and their medicinal qualities

Kumar, Vijay; Singh, Simranjeet; Kondalkar, Sapna Avinash; Srivastava, Bhavana; Sisodia, Brijesh S.; Barthi, Bandana; Singh, Ravindara; Prakash, Om

doi:10.1016/j.bcab.2019.101405

Cited by 19 publications

(23 citation statements)

References 23 publications

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“…Indian traditional medicine system which includes Ayurveda, Siddha, Unani, Yoga, Naturopathy and Homeopathy can treat wide class of diseases. Indian medicine system is more than 5000 years old and well documented system [ [63] , [64] , [65] , [66] , [67] , [68] , [69] , [70] ]. The major sources of drugs of Indian Medicine System are plants, minerals and animal products.…”

Section: Medicines Against Covid-19mentioning

confidence: 99%

“…It has been reported that SARS-CoV-2 mainly transmitted through nose and throat [ 86 , 87 ]. Herbs of Indian Medicine System like Crocus sativus L., Emblica officinalis , Ocimun sanctum , Tinospora cordifolia , Curcuma longa L., Trachyspermum ammi, Piper longum and Zingiber officinale may reduce the risk of throat infection and kill microorganisms [ [65] , [66] , [67] , [68] , [69] , [70] , [71] , [72] , [73] , [74] , [75] , [76] , [77] , [78] ]. Application of Glycyrrhiza glabra , Trachyspermum ammi , and honey are well mentioned in Ayurveda for throat infection [ 85 , 88 ].…”

Section: Medicines Against Covid-19mentioning

confidence: 99%

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COVID-19: Environment concern and impact of Indian medicinal system

Kumar¹,

Singh²,

Singh

2020

Journal of Environmental Chemical Engineering

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Section: Medicines Against Covid-19mentioning

confidence: 99%

Section: Medicines Against Covid-19mentioning

confidence: 99%

COVID-19: Environment concern and impact of Indian medicinal system

Kumar¹,

Singh²,

Singh

2020

Journal of Environmental Chemical Engineering

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“…1,3 Quantitative analysis of phytochemicals was done by using direct mass study. [13][14][15][16][17]…”

Section: Physicochemical and Phytochemical Analysismentioning

confidence: 99%

“…Antioxidant assays, viz., nitric oxide scavenging activity, ferric-reducing power estimation, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay, ferric-reducing antioxidant power (FRAP) assay, metal-chelating activity assay, scavenging activity of superoxide anion assay, and phosphomolybdenum antioxidant assay of various extracts were performed per our recent reports. [13][14][15][16][17] Also, bovine serum albumin (BSA) protein-binding ability of various extracts was assessed per our recent reports. [13][14][15][16][17]…”

Section: Biochemical Assaysmentioning

confidence: 99%

“…Recent studies revealed that BC is an important plant as it helps in wound-healing, gastric ulcer treatment and has antistress, antidiarrheal, anti-venom, antimicrobial, antioxidant anti-inflammatory, analgesic, and anti-Alzheimer properties. [5][6][7][8][9][10][11][12][13][14][15][16][17] During the course of our study of the biologically active constituents of BC, we examined the chemical constituents of the small branches (SBs) and stem bark (STB) in various extracts. In the current study, we investigated the phytochemical, antioxidant, and antimicrobial properties of the extracts (petroleum ether, acetone, and methanol) of SB and STB obtained from BC.…”

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Comparative Assessment of Phytochemicals, Antioxidant, and Antimicrobial Potential of Stem Bark and Small Branches of Buchanania cochinchinensis (Lour.) MR Almeida for Substitution in Ayurvedic Drugs

Dixit¹,

Kumar²,

Maloni³

et al. 2019

Journal of Drug Research in Ayurvedic Sciences

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Aim: Present study was intended to investigate the physicochemical parameters, phytochemical constituents, and biochemical studies of the stem bark (STB) and small branches (SBs) of Buchanania cochinchinensis (Lour.) MR Almeida. Materials and methods: The parameters were checked in different solvent systems, viz., petroleum ether, acetone, and methanol. Results: Significant antioxidant (10-85%) and antimicrobial (5-20 mm) activities were observed in acetone and methanolic extracts of STB and SB as compared to the controls. In acetone and methanolic extracts, the observed values for total phenol content (TPC) ranged from 10 mg to 93 mg of gallic acid equivalent per gram of extract and the total flavonoid content (TFC) ranged from 30 mg to 87 mg of quercetin equivalent (QE) per gram of extract. Bovine serum albumin (BSA) protein interaction studies of all the extracts were performed and the observed values for binding constant ranged from 22 to 62 × 10 − 5 μM − 1 . Conclusion: Overall, acetone and methanolic extracts of STB and SB of plant have shown significant results in medicinal aspects mentioned above. Clinical significance: These comparative findings of STB and SB of Buchanania cochinchinensis (Lour.) MR Almeida provide undeniable systematic facts of its beneficial prospective as an Ayurvedic drug.

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Quantification of Phytochemicals and Metal Ions as well as the Determination of Volatile Compounds, Antioxidant, Antimicrobial and Antacid Activities of the Mimosa pudica L. Leaf: Exploration of Neglected and Under‐Utilized Part

Gandhi,

Prasad,

Kumar

et al. 2023

Chemistry & Biodiversity

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Mimosa pudica L. (MP) is well‐known plant in traditional medicinal system, especially in India. Unfortunately, leaves of MP are less explored. To determine the food and nutritional value of the neglected part of Mimosa pudica L. (MP), that is MP leaves, phytochemicals and metal ions of MP were quantified by newly developed HPLC and ICPOES‐based methods. The content of phytochemicals observed using HPLC analysis for chlorogenic acid, catechin, and epicatechin was 141.823 (±8.171), 666.621 (±11.432), and 293.175 (±12.743) μg/g, respectively. Using GC/MS/MS analysis, fatty acid like oleic acid were identified. In ICP‐OES analysis, a significant content of Na, K, Ca, Cu, Fe, Mg, Mn, and Zn was observed. The observed TPC and TFC for MP leaf extracts was 44.327 (±1.041) mg GAE/ g of wt. and 214.217 (±4.372) mg QCE/ g of wt., respectively. The DPPH assay depicted a strong antioxidant activity of MP leaf extracts with IC50 values of 0.796 (±0.081) mg/mL and a TEAC value of 0.0356 (±0.0003). A significant antacid activity (666 mg MP+400 mg CaCO3 >400 mg CaCO3 ≫666 mg Gelusil) of MP leaves was noticed. The methanolic extract of MP leaves demonstrated anti‐microbial activity against Staphylococcus aureus (15±2mm), Pseudomonas aeruginosa (12±2mm) and Escherichia coli (10±2mm). In silico studies confirmed the in vitro results obtained for antioxidant, antiacid, and anti‐microbial activities. In addition, in silico studies revealed the anti‐cancerous and anti‐inflammatory potential of the MP leaves. In summary, this study demonstrated the medicinal significance of MP leaves and the conversion of agro‐waste or the under‐utilized part of MP into pharmaceutical potent materials. Consequently, the present study highlighted that MP leaves alone have medicinal importance with good nutritional utility and possess large promise in the pharma industry along with improving bio‐valorization and the environment.

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High resolution GC/MS analysis of the Holoptelea integrifoli's leaves and their medicinal qualities

Cited by 19 publications

References 23 publications

COVID-19: Environment concern and impact of Indian medicinal system

COVID-19: Environment concern and impact of Indian medicinal system

Comparative Assessment of Phytochemicals, Antioxidant, and Antimicrobial Potential of Stem Bark and Small Branches of Buchanania cochinchinensis (Lour.) MR Almeida for Substitution in Ayurvedic Drugs

Quantification of Phytochemicals and Metal Ions as well as the Determination of Volatile Compounds, Antioxidant, Antimicrobial and Antacid Activities of the Mimosa pudica L. Leaf: Exploration of Neglected and Under‐Utilized Part

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