2018
DOI: 10.1111/nmo.13505
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High‐resolution impedance manometry parameters in the evaluation of esophageal function of non‐obstructive dysphagia patients

Abstract: Background High‐resolution impedance manometry (HRIM) allows evaluation of esophageal bolus retention, flow, and pressurization. We explored novel HRIM measures and assessed their temporal relationship to dysphagia symptoms for boluses of different volume and consistency in non‐obstructive dysphagia (NOD) patients. Methods Thirty‐three NOD patients (n = 19 minor or no disorder of peristalsis (“Normal”) and n = 14 esophagogastric junction outflow obstruction (“EGJOO”)) were evaluated with HRIM. Patients were ad… Show more

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Cited by 22 publications
(18 citation statements)
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“…• A manometric diagnosis of EGJOO is defined as an elevated median IRP in the primary and secondary position and ≥20% swallows with elevated intrabolus pressure in the supine position, with evidence of peristalsis (Low GRADE, Conditional Recommendation). 11,18,46,50,51,[53][54][55] •…”
Section: Clinically Relevant Conclusive Diagnosis Of Egjoomentioning
confidence: 99%
See 1 more Smart Citation
“…• A manometric diagnosis of EGJOO is defined as an elevated median IRP in the primary and secondary position and ≥20% swallows with elevated intrabolus pressure in the supine position, with evidence of peristalsis (Low GRADE, Conditional Recommendation). 11,18,46,50,51,[53][54][55] •…”
Section: Clinically Relevant Conclusive Diagnosis Of Egjoomentioning
confidence: 99%
“… A manometric diagnosis of EGJOO is always considered clinically inconclusive (Strong Recommendation). A manometric diagnosis of EGJOO is defined as an elevated median IRP in the primary and secondary position and ≥20% swallows with elevated intrabolus pressure in the supine position, with evidence of peristalsis (Low GRADE, Conditional Recommendation) 11,18,46,50,51,53–55 A clinically relevant conclusive diagnosis of EGJOO requires a manometric diagnosis of EGJOO and clinically relevant symptoms with at least one of the following supportive investigations supporting obstruction (TBE, preferably in conjunction with a barium tablet swallow, and/or FLIP) (Moderate GRADE, Conditional Recommendation) 11–13,18,37 …”
Section: Egj Outflow Obstructionmentioning
confidence: 99%
“…However, these results confirm that symptoms are not driven solely by the vigor or frequency of abnormal esophageal contractions; the other peripheral or central factors that participate in symptom perception in these patients need to be determined. High‐resolution impedance manometry that allows evaluation of esophageal bolus retention, flow, and pressurization might be useful to better understand the mechanism of dysphagia in patients with JE, as it has been recently reported in patients with achalasia and in patients with non‐obstructive dysphagia related to esophagogastric junction outflow obstruction 24,25 …”
Section: Discussionmentioning
confidence: 99%
“…High‐resolution impedance manometry is recommended, though not required by CCv4.0, to assess not only pharyngeal function, but also intra‐bolus pressure and bolus clearance through the EGJ. This combined technology is the subject of separate articles 11‐13 …”
Section: Methodsmentioning
confidence: 99%