High‐Sensitive Sensor of Dopamine Based on Photoluminescence Quenching of Hierarchical CdS Spherical Aggregates

Abstract

Hierarchical CdS spherical aggregates have been fabricated by an assembling strategy starting from nanoparticles, which opens a general way to obtain hierarchical spherical aggregates of different types of materials. The hierarchical CdS spherical aggregates are of high porosity and high surface area, which give rise to unique photoluminescence properties. The desirable properties we report here will spur further developments of novel dopamine photoluminescence sensors based on the high surface area hierarchical CdS spherical aggregates fabricated with our unique assembling strategy. The novel dopamine photoluminescence sensor has a low detection limit of1.0×10−8 M, which is much lower than those reported previously.

Advanced materials for optical sensing and biosensing of neurotransmitters

“…Sun et al employed hierarchically-sensitized CdS aggregates for determination of DA with an LOD of 1.0 × 10 −8 M. Quenching of the PL emissions of CdS by DA was expected via the nonradiative pathways aided by the oxidized form of DA. An advantage of these materials is that the quenched fluorescence is located at NIR of 700 nm that is somewhat free from possible interferences [18,24]. Fig.…”

Recent Advances in Electrochemical and Optical Sensing of Dopamine

“…many critical roles in human health related to the central nervous, renal, cardiovascular, and hormonal systems, and other animals including both vertebrates and invertebrates [1][2][3][4][5][6]. In the late 1950s, DA was discovered to be a NT by Arvid Carlsson [7,8]. The adrenal gland and specific areas of the brain are responsible for the secretion and release of DA.…”

“…Suitable sensors for clinical diagnostics of DA require detection limits in the order of the nanomolar level. In the late 1950s, DA was discovered to be a NT by Arvid Carlsson [7,8]. The adrenal gland and specific areas of the brain are responsible for the secretion and release of DA.…”

New Trends in Fluorescent Nanomaterials-Based Bio/Chemical Sensors for Neurohormones Detection─A Review

“…On the other hand, low concentrations are typical of Parkinson’s disease, schizophrenia, Alzheimer’s disease, and depression. 140 − 143 , 179 , 180 …”

“…High levels of DA can be observed in the presence of cardiotoxicity, which can lead to rapid heartbeat rate, hypertension, and also heart failure. On the other hand, low concentrations are typical of Parkinson’s disease, schizophrenia, Alzheimer’s disease, and depression. − ,, …”