High Sensitivity C-Reactive Protein as a Potential Biomarker of Neuroinflammation in Major Psychiatric Disorders

Padovan, Giordano; Preteroti, Rosa; Bortolato, Beatrice; Papaioannou, Maria; Piva, Giada; Magnolfi, Gianna

doi:10.2174/1573396314666180710150541

Search citation statements

Order By: Relevance

Paper Sections

Select...

Introduction1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2021

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In turn, proinflammatory cytokines can cross the Blood Brain Barrier (BBB) to enter the brain and to trigger neuroinflammation in addition to prompting BBB disruption. CRP also contributes to the leakage of the BBB [ 3 ] and has been positioned as a potential biomarker of neuroinflammation in major psychiatric disorders [ 12 , 13 ].…”

Section: Introductionmentioning

confidence: 99%

Inflammatory Biomarkers in Addictive Disorders

Morcuende¹,

Navarrete

Nieto³

et al. 2021

Biomolecules

View full text Add to dashboard Cite

Substance use disorders are a group of diseases that are associated with social, professional, and family impairment and that represent a high socio-economic impact on the health systems of countries around the world. These disorders present a very complex diagnosis and treatment regimen due to the lack of suitable biomarkers supporting the correct diagnosis and classification and the difficulty of selecting effective therapies. Over the last few years, several studies have pointed out that these addictive disorders are associated with systemic and central nervous system inflammation, which could play a relevant role in the onset and progression of these diseases. Therefore, identifying different immune system components as biomarkers of such addictive disorders could be a crucial step to promote appropriate diagnosis and treatment. Thus, this work aims to provide an overview of the immune system alterations that may be biomarkers of various addictive disorders.

show abstract

Section: Introductionmentioning

confidence: 99%