High-Sensitivity PtSe2 Surface Plasmon Resonance Biosensor Based on Metal-Si-Metal Waveguide Structure

Lin, Zhitao; Shu, Yiqing; Chen, Wei-Cheng; Zhao, Yang; Li, Jianqing

doi:10.3390/bios12010027

Cited by 7 publications

(7 citation statements)

References 43 publications

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“…An increase in the thickness of the PtSe 2 layer beyond 2 layers results in a rapid transformation of the reflectance curve, rendering it broader and shallower. This phenomenon is associated with the diminishing electric field distribution at the interface between the sensor and the sensing medium, as demonstrated by [49]. This insignificant minimum reflectance poses challenges in signal readability due to susceptibility to distortion from noise.…”

Section: Resultsmentioning

confidence: 99%

Enhancing urine glucose sensing performance through the introduction of two dimensional-transition metal dichalcogenides and gold nanoparticles into silver/UiO-66 chip of surface plasmon resonance

Tiandho,

Afriani,

Septiani

et al. 2024

Nanotechnology

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This work presents a high-performance surface plasmon resonance (SPR)-based biosensor for glucose detection. While adding a metal-organic framework (MOF) layer, UiO-66, to the biosensor improves selectivity and enables direct detection without additional receptors, it does not significantly enhance sensitivity. A SPR-based biosensor is proposed to overcome this limitation by introducing a layer of 2D-transition metal dichalcogenides (2D-TMD) and decorating the UiO-66 structure with gold nanoparticles (UiO-66AuNP). The optical properties of the biosensor for glucose detection in urine are investigated by employing the finite difference time domain (FDTD) method with Kretschmann configuration at a wavelength of 633 nm, and its performance is effectively improved by incorporating 2D-TMD and AuNP layers into the biosensor structure. Notably, the SPR-based biosensor with the decorated UiO-66 layer exhibits a further change in the SPR angle in the presence of glucose-containing urine. Using computational studies, various performance parameters, such as the biosensors' signal-to-noise ratio (SNR) and quality factor (QF), are evaluated in addition to sensitivity. The maximum sensitivity achieved is 309.3°/RIU for the BK7/Ag/PtSe2/WSe2/MoS2/UiO-66AuNP/sensing medium structure. The exceptional performance of the proposed biosensor structure demonstrates its suitability for precise glucose detection in urine while also opening new avenues for developing bioreceptor-free SPR-based sensors.

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Section: Resultsmentioning

confidence: 99%

Enhancing urine glucose sensing performance through the introduction of two dimensional-transition metal dichalcogenides and gold nanoparticles into silver/UiO-66 chip of surface plasmon resonance

Tiandho,

Afriani,

Septiani

et al. 2024

Nanotechnology

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“…Here, a bilayer of Ag with optimized thicknesses separated by a Si spacer layer is regarded which forms a metal-insulator-metal configuration. To increase the propagation distance of the surface plasmon wave, adding a planar waveguide is an effective method for elimination of the metal damping [49].…”

Section: Resultsmentioning

confidence: 99%

Highly efficient MIM based SPR sensor for glucose detection using blueP/WS₂ layers

Sarafraz,

Noori

2024

Phys. Scr.

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In this article, a highly efficient surface plasmon resonance sensor for glucose detection in urine biosamples is presented. The proposed structure with the Ag-Si-Ag configuration was investigated and optimized using the transfer matrix method. In addition, blueP/WS2 and ZnO layers were implemented to further improve the sensitivity of the sensor by light-mater interaction enhancement in the sensing layer. The multilayer configuration of the optimized sensor consists of SiO2 prism /ZnO /Ag1/ Si/Ag2 /ZnO /blueP/WS2 layers, respectively and operates at λ=633 nm. Different glucose concentrations of 0 to 15 mg/dl (for non-diabetic person), 0.625 gm/dL, 1.25 gm/dL, 2.5 gm/dL, 5 gm/dL, and 10 gm/dL (for diabetic body), with refractive indices of 1.335, 1.336, 1.337, 1.338, 1.341, and 1.347, respectively have been regarded and the qualification parameters of S=320 deg/RIU, FWHM=1.5767 deg, FOM=215.99 RIU-1, and minimum reflectance of 0.0318 have been evaluated. We believe that the proposed sensor could pave the way to easy and accurate detection of glucose concentration which is vital in control or treatment of diabetes.

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“…Its thickness affects sensitivity, FWHM, DA, and QF. Most recent works show that ,, sensor performance can be enhanced by optimizing the PtSe 2 thickness. Here, we have analyzed the thickness-dependent sensor performance to optimize the PtSe 2 thickness.…”

Section: Resultsmentioning

confidence: 99%

Design and Analysis of PtSe₂ and Blue Phosphorus/MoS₂ Heterostructure-Based SPR Biosensor

Chowdhury,

Islam,

Islam

et al. 2024

ACS Appl. Opt. Mater.

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Biosensors using surface plasmon resonance (SPR) have emerged as effective tools for accurate and instantaneous sensing applications. Nevertheless, optimizing sensor configurations continues to be of utmost importance to attain dependable sensing capabilities. This work presents an intriguing design structure that integrates conventional SPR technology with PtSe 2 and blue phosphorus−MoS 2 heterostructure, resulting in an improved and adaptable sensing technology. The finite-difference timedomain (FDTD) method was used to model and design the prospective sensor. The proposed design has notable attributes, such as an extraordinarily narrow full width at half-maximum (FWHM) of 8.23°, small detection accuracy of 0.1215, an extraordinary sensitivity of 240.54°/RIU, and an outstanding quality factor of 29.23 RIU −1 . Significantly, this sensor has a sensitivity that is 3.2 times higher than that of traditional gold-based SPR sensors. In addition, the sensor provides a broad observable range of refractive indices, ranging from 1.33 to 1.36. The broad spectrum of this detection system allows for the identification of diverse ambient chemicals, such as alcohol, ethanol, and water, as well as biomolecules, including urine, glucose, and DNA hybridization. These results represent a significant stride forward for SPR biosensors, allowing for the creation of high-performance sensing systems with a wide range of potential uses.

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High-Sensitivity PtSe2 Surface Plasmon Resonance Biosensor Based on Metal-Si-Metal Waveguide Structure

Cited by 7 publications

References 43 publications

Enhancing urine glucose sensing performance through the introduction of two dimensional-transition metal dichalcogenides and gold nanoparticles into silver/UiO-66 chip of surface plasmon resonance

Enhancing urine glucose sensing performance through the introduction of two dimensional-transition metal dichalcogenides and gold nanoparticles into silver/UiO-66 chip of surface plasmon resonance

Highly efficient MIM based SPR sensor for glucose detection using blueP/WS₂ layers

Design and Analysis of PtSe₂ and Blue Phosphorus/MoS₂ Heterostructure-Based SPR Biosensor

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High-Sensitivity PtSe2 Surface Plasmon Resonance Biosensor Based on Metal-Si-Metal Waveguide Structure

Cited by 7 publications

References 43 publications

Enhancing urine glucose sensing performance through the introduction of two dimensional-transition metal dichalcogenides and gold nanoparticles into silver/UiO-66 chip of surface plasmon resonance

Enhancing urine glucose sensing performance through the introduction of two dimensional-transition metal dichalcogenides and gold nanoparticles into silver/UiO-66 chip of surface plasmon resonance

Highly efficient MIM based SPR sensor for glucose detection using blueP/WS2 layers

Design and Analysis of PtSe2 and Blue Phosphorus/MoS2 Heterostructure-Based SPR Biosensor

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Highly efficient MIM based SPR sensor for glucose detection using blueP/WS₂ layers

Design and Analysis of PtSe₂ and Blue Phosphorus/MoS₂ Heterostructure-Based SPR Biosensor