High speed counter current chromatography: A support-free LC technique

Sethi, Neha; Anand, Ankit; Sharma, Aarti; Chandrul, Kaushal K.; Jain, Garima; Srinivasa, Kona S

doi:10.4103/0975-7406.62680

Cited by 11 publications

(1 citation statement)

References 5 publications

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“…High‐speed counter‐current chromatography (HSCCC) with a 2‐phase solvent system once gained attention in the field of polyphenol purifications and separation. However, it was later found to be difficult to optimize due to several limitations (Sethi et al., ). In recent times, macroporous adsorption resins (MARs) are being widely used to remove impurities and increase recovery of bioactives in complex mixtures (Pan et al., ; Yang, Zhao, & Lin, ).…”

Section: Factors Affecting Variations In Flavonoids and Phenolic Acidsmentioning

confidence: 99%

Lotus Flavonoids and Phenolic Acids: Health Promotion and Safe Consumption Dosages

Limwachiranon

Huang

Shi

et al. 2018

Comp Rev Food Sci Food Safe

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Nelumbo nucifera Gaertn., also known as the sacred lotus, is extensively cultivated in Southeast Asia, primarily for food and as an herbal medicine. This article reviews studies published between 1995 and 2017, on flavonoid and phenolic acid profiles and contents of 154 different cultivars of lotus. So far, some 12 phenolic acids and 89 to 90 flavonoids (47 flavonols, 25 to 26 flavons, 8 flavan-3-ols, 4 flavanons, and 5 anthocyanins) have been isolated from different parts of the lotus plant, including its leaves (whole leaf, leaf pulp, leaf vein, and leaf stalk), seeds (seedpod, epicarp, coat, kernel, and embryo), and flowers (stamen, petal, pistil, and stalk), although not all of them have been quantified. Factors affecting flavonoids and phenolic acid profiles, including types of tissues and extracting factors, are discussed in this review, in order to maximize the application of the lotus and its polyphenols in the food industry. Health promotion activities, attributed to the presence of flavonoids and phenolic acids, are described along with toxicology studies, illustrating appropriate usage and safe consumption dosages of lotus extracts. This review also presents the controversies and discusses the research gaps that limit our ability to obtain a thorough understanding of the bioactivities of lotus extracts.

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Section: Factors Affecting Variations In Flavonoids and Phenolic Acidsmentioning

confidence: 99%

Lotus Flavonoids and Phenolic Acids: Health Promotion and Safe Consumption Dosages

Limwachiranon

Huang

Shi

et al. 2018

Comp Rev Food Sci Food Safe

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Minor Components in Edible Oil

Chong

Lee

Tang

et al. 2022

Recent Advances in Edible Fats and Oils Technology

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Separation and purification of bioactive botrallin and TMC-264 by a combination of HSCCC and semi-preparative HPLC from endophytic fungus Hyalodendriella sp. Ponipodef12

Mao

Luo

et al. 2014

World J Microbiol Biotechnol

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Two dibenzo-α-pyrones, botrallin (1) and TMC-264 (2) were preparatively separated from crude ethyl acetate extract of the endophytic fungus Hyalodendriella sp. Ponipodef12, which was isolated from the hybrid 'Neva' of Populus deltoides Marsh × P. nigra L. using a combination of high-speed counter-current chromatography (HSCCC) and semi-preparative HPLC. Botrallin (1) with 74.73% of purity and TMC-264 (2) with 82.29% of purity were obtained through HSCCC by employing a solvent system containing n-hexane-ethyl acetate-methanol-water at a volume ratio of 1.2:1.0:0.9:1.0. It was the first time for TMC-264 (2) to be isolated from this fungus. TMC-264 (2) showed strong antimicrobial and antinematodal activity, and botrallin (1) exhibited moderate inhibitory activity on acetylcholinesterase.

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High speed counter current chromatography: A support-free LC technique

Cited by 11 publications

References 5 publications

Lotus Flavonoids and Phenolic Acids: Health Promotion and Safe Consumption Dosages

Lotus Flavonoids and Phenolic Acids: Health Promotion and Safe Consumption Dosages

Minor Components in Edible Oil

Separation and purification of bioactive botrallin and TMC-264 by a combination of HSCCC and semi-preparative HPLC from endophytic fungus Hyalodendriella sp. Ponipodef12

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