High‐Strength and Injectable Supramolecular Hydrogel Self‐Assembled by Monomeric Nucleoside for Tooth‐Extraction Wound Healing (Adv. Mater. 13/2022)

Abstract

In article number 2108300, Hang Zhao, Xianglong Han, Qianming Chen, and co-workers introduce a high-strength and injectable supramolecular hydrogel, which was constructed by the selfassembly of a monomeric nucleoside molecular gelator (2-amino-2'-fluoro-2'-deoxyadenosine, 2-FA). Notably, it also exhibits excellent biocompatibility, fast biodegradation, antibacterial properties, and osteoclast inhibition, making it a potential candidate biomaterial for tooth-extraction wound healing and tissue engineering.

A chitosan-optimized polyethyleneimine/polyacrylic acid multifunctional hydrogel for reducing the risk of ulcerative arterial bleeding

“…Although hydrogen bonds are weak noncovalent bonds, hydrogen bond synergies have a strengthening effect similar to covalent bonds. [41][42][43] At the same time, CS is positively charged and can bind with negatively charged PAA. The above results indicate that the PEI/PAA/CS hydrogel could adhere to the ulcer surface to form a physical barrier to protect the wound and isolate the erosion of digestive tract contents to reduce the risk of ulcer artery bleeding.…”

Injectable hydrogels as emerging drug-delivery platforms for tumor therapy

“…The remarkable energy storage modulus, reaching 1 MPa at a concentration of 5.0 wt%, positions it as the strongest supramolecular hydrogel containing an ultra-low molecular weight (MW < 300) gelling agent. 47 Inspired by the slow transformation of mineral precursors during biomineralization, Li proposed a general endogenous gelation method for tannic acid-macromolecule hydrogels. The method controls the elimination or slow generation of hydrogen bonding interactions between tannins and macromolecules by regulating the pH value of the system.…”

Biodegradable Nanoflowers with Abaloparatide Spatiotemporal Management of Functional Alveolar Bone Regeneration

“…Adverse consequences including prolonged treatment time, odontoseisis, root exposure or even tooth loss might take place during OTM. Thus, encouraging the restoration of both morphologically and functionally active alveolar bone via biomaterial-based bone regeneration has gained prominence.…”