Higher coronary artery calcification score is associated with adverse prognosis in patients with stable angina pectoris

Wang, Renrong; Liu, Huan; Wang, Chunxia; Ye, Xinhe; Xu, Xin; Yang, Chengjian

doi:10.21037/jtd.2017.02.84

Cited by 16 publications

(19 citation statements)

References 23 publications

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“…As recurrent MR after MVP is associated with progressive LV remodeling, durable mitral competence after customized MVP must contribute to LV reverse remodeling. 2 , 14 – 16) This is in line with the findings of a systematic review on SVP by Mihos et al and Athanasopoulos et al 17 , 18) Although we used several different SVPs and recognized the advantages and disadvantages of each technique, the different SVPs would offer similar mitral competence. 18 , 19) …”

Section: Discussionsupporting

confidence: 84%

“… 20) A systematic review and meta-analysis by Mihos et al and a prospective randomized trial by Nappi et al demonstrated that adding SVP to MAP for ischemic MR was associated with greater LV reverse remodeling and less recurrence of moderate or greater MR than those achieved by MAP alone; however, no difference was found in the mortality rate. 12 , 17) Therefore, it is unclear whether achieving good mitral competence following elaborate MV surgery always guarantees improved survival in FMR.…”

Section: Discussionmentioning

confidence: 99%

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Clinical Outcomes of a Customized Mitral Valve Plasty for Functional Mitral Regurgitation with a Low Ejection Fraction and Implications for Preoperative Right Ventricular Function

Furukawa

Yano²,

Ishii

et al. 2021

ATCS

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Purpose: To evaluate clinical outcomes of customized mitral valve plasty (MVP) for the treatment of functional mitral regurgitation (FMR) with a low ejection fraction (EF) and to determine which preoperative factors affected the clinical outcome. Methods and Results: MVP was adjusted according to the degree of left ventricle (LV) remodeling. We performed mitral annuloplasty (MAP) alone in 14 patients and added subvalvular procedures (SVPs) in 22 patients at a high risk of recurrent MR. During follow-up, reverse LV remodeling was obtained and the 3-year and 5-year non-recurrence rates of MR grade ≥2 were 94% and 89%, respectively. Two patients died during their hospital stay, and four more patients died of cardiac causes during follow-up. The 3-year and 5-year rates of freedom from cardiac-related mortality were 86% and 81%, respectively; no significant difference was observed between the two treatment groups. Right ventricular fractional area change (RVFAC) was a significant predictor of cardiac mortality. Patients with an RVFAC of <26% had significantly poorer cardiac-related mortality (71% at 3 years) than those with an RVFAC of ≥26% (95% at 3 years). Conclusion: Customized MVP provided durable mitral competence and reverse LV remodeling. Preoperative RV function was associated with cardiac-related mortality.

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Section: Discussionsupporting

confidence: 84%

Section: Discussionmentioning

confidence: 99%

Clinical Outcomes of a Customized Mitral Valve Plasty for Functional Mitral Regurgitation with a Low Ejection Fraction and Implications for Preoperative Right Ventricular Function

Furukawa

Yano²,

Ishii

et al. 2021

ATCS

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“…A CAC score of 0 in patients with suspected stable angina has a high negative predictive value for the exclusion of obstructive coronary artery disease and is associated with a good medium-term prognosis [ 13 ]. The CAC scores and major adverse cardiac events are strongly and positively correlated in patients with stable angina [ 14 ]. Two recognized types of CAC are intimal and medial artery calcification [ 15 ].…”

Section: Discussionmentioning

confidence: 99%

Association of Bone Mineral Density and Coronary Artery Calcification in Patients with Osteopenia and Osteoporosis

2020

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The aim of this study was to investigate the association between bone mineral density (BMD) and coronary artery calcification (CAC) in adults with osteopenia or osteoporosis. A retrospective medical review study was conducted in a regional hospital in southern Taiwan. Medical records of patients who underwent both a coronary computed tomography scan and a BMD measurement were identified. Multinomial logistic regression analyses were used to assess the association between BMD and CAC levels in patients with osteopenia or osteoporosis. Of the 246 patients, 119 were female and 42.3% had CAC. For patients with osteopenia, after adjusting for the significant factors of CAC, no significant association was observed between BMD with either moderate CAC (0 < CAC score ≤ 100) or high CAC (CAC score > 100). However, in patients with osteoporosis, after adjusting for the significant factors of CAC, BMD in the lumbar spine was inversely associated with moderate CAC (odds ratio = 0.38, p = 0.035). In conclusion, a lower BMD in the lumbar spine was associated with an increased risk of moderate CAC in patients with osteoporosis. It is crucial to take action to maintain bone health, particularly in those who already have osteoporosis, to reduce the risk of developing CAC and its associated morbidity and mortality.

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“…10 In addition to angiographic assessment of CAC severity, CAC scoring is a cardiac computed tomography (CT)-based methodology to evaluate the amount of calcium within coronary arteries, the role of which in predicting long-term future clinical events in patients with and without coronary artery disease has been evaluated in previous studies. [16][17][18][19][20] Although CAC scoring is a reliable, reproducible and predictive score of cardiovascular risk, 21 it is dependent on results of cardiac CT. On the other hand, intravascular imaging techniques, including IVUS and optical coherence tomography (OCT), are considered as essential gold standards for coronary calcium detection. 22 However, not all patients undergoing PCI have IVUS or OCT assessment during the procedure or have recently undergone cardiac CT scan.…”

Section: Study Limitationsmentioning

confidence: 99%

Long-Term Prognosis of Moderate to Severe Coronary Artery Calcification in Patients Undergoing Percutaneous Coronary Intervention

Jia

Zhang

et al. 2020

Circ J

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Higher coronary artery calcification score is associated with adverse prognosis in patients with stable angina pectoris

Cited by 16 publications

References 23 publications

Clinical Outcomes of a Customized Mitral Valve Plasty for Functional Mitral Regurgitation with a Low Ejection Fraction and Implications for Preoperative Right Ventricular Function

Clinical Outcomes of a Customized Mitral Valve Plasty for Functional Mitral Regurgitation with a Low Ejection Fraction and Implications for Preoperative Right Ventricular Function

Association of Bone Mineral Density and Coronary Artery Calcification in Patients with Osteopenia and Osteoporosis

Long-Term Prognosis of Moderate to Severe Coronary Artery Calcification in Patients Undergoing Percutaneous Coronary Intervention

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