Higher Pain Sensitivity Predicts Efficacy of a Wearable Transcutaneous Electrical Nerve Stimulation Device for Persons With Fibromyalgia: A Randomized Double-Blind Sham-Controlled Trial

Jamison, Robert N.; Curran, Samantha; Wan, Limeng; Ross, Edgar L.; Gilligan, Christopher; Edwards, Robert R.

doi:10.1111/ner.13463

Cited by 4 publications

(5 citation statements)

References 56 publications

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“…The risk of bias assessment for included studies using PEDro scale is presented in Supplemental file, Table S3. Thirty-four studies 38–71 showed a PEDro score >5, 16 studies 36,37,72–85 scored 5, and the remaining four 86–89 scored 4. The overall mean (SD) PEDro score was 6.57 (1.73).…”

Section: Resultsmentioning

confidence: 98%

“…Forty-seven studies 36,37,39,41–52,54–61,63,65–79,81–88 assessed pain and were eligible for network meta-analysis of pain (Figure 2). When compared to placebo, the consistency model of the network showed that transcutaneous electrical nerve stimulation ( P = 0.006) and microcurrent ( P = 0.037) improved pain symptoms significantly.…”

Section: Resultsmentioning

confidence: 99%

“…Data on functional status were available from 32 studies, but one study was removed because none of its treatment arm was connected with placebosham or any other in the mood network; hence, 31 studies 38,[40][41][42]44,[48][49][50][53][54][55][56]59,[61][62][63][64]66,67,69,71,72,[75][76][77][79][80][81]84,87,89 were eligible for network meta-analysis (Figure 3). The consistency model showed that when compared to placebo, only repetitive transcranial magnetic stimulation (P = 0.018) improved patient functional status significantly after the intervention (Table 3).…”

Section: Functional Statusmentioning

confidence: 99%

“…Twenty-six studies 40,41,43,[48][49][50][52][53][54][55][56][57]61,[65][66][67][68][69]72,74,75,77,82,84,88,89 assessed mood and were eligible for NMA of pain (Figure 4). The consistency model of the network showed that when compared to placebo, microcurrent (P = 0.001), repetitive transcranial magnetic stimulation (P = 0.022), and no treatment (P = 0.038) significantly improved mood after intervention (Table 3).…”

Section: Moodmentioning

confidence: 99%

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Efficacy of electrophysical agents in fibromyalgia: A systematic review and network meta-analysis

et al. 2023

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Objective To examine the effectiveness of electrophysical agents in fibromyalgia. Data sources CINAHL, Cochrane Library, Embase, Medline, PEDro, and Web of Science were searched from their inceptions to March 27, 2023. Methods This study was registered in PROSPERO (CRD42022354326). Methodological quality of included trials was assessed using PEDro scale, and the quality of evidence was determined according to the Grading of Recommendations Assessment, Development, and Evaluation system. The primary outcomes were pain, functional status, and mood. Results Fifty-four studies involving 3045 patients with fibromyalgia were eligible for qualitative synthesis and 47 (pain), 31 (functional status), and 26 (mood) for network meta-analysis. The network consistency model revealed that, when compared with true control, transcutaneous electrical nerve stimulation and microcurrent improved pain symptoms ( P = 0.006 and P = 0.037, respectively); repetitive transcranial magnetic stimulation improved patient functional status ( P = 0.018); and microcurrent ( P = 0.001), repetitive transcranial magnetic stimulation ( P = 0.022), and no treatment ( P = 0.038) significantly improved mood after intervention. Surface under the cumulative ranking indicated that microcurrent was most likely to be the best for managing pain and mood (surface under the cumulative ranking: 70% and 100%, respectively); low-level laser therapy for pain and mood (80% and 70%, respectively); and repetitive transcranial magnetic stimulation for improving functional status and mood (80% and 70%, respectively). Conclusion This review found low to moderate quality evidence that microcurrent, laser therapy, and repetitive transcranial magnetic stimulation are the most effective electrophysical agents for improving at least one outcome in fibromyalgia.

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Section: Resultsmentioning

confidence: 98%

Section: Resultsmentioning

confidence: 99%

Section: Functional Statusmentioning

confidence: 99%

Section: Moodmentioning

confidence: 99%

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Efficacy of electrophysical agents in fibromyalgia: A systematic review and network meta-analysis

et al. 2023

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“… 19 Interestingly, recent studies of high-frequency TENS treatment for musculoskeletal pain report that patients who are most sensitive to mechanical noxious stimuli are more likely to benefit from active TENS treatment relative to sham/placebo. 98 , 100 , 102 …”

Section: Resultsmentioning

confidence: 99%

Optimizing and Accelerating the Development of Precision Pain Treatments for Chronic Pain: IMMPACT Review and Recommendations

Edwards¹,

Schreiber²,

Dworkin³

et al. 2023

The Journal of Pain

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Influence of Transcutaneous Electrical Nerve Stimulation (TENS) on Pressure Pain Thresholds and Conditioned Pain Modulation in a Randomized Controlled Trial in Women With Fibromyalgia

Berardi,

Dailey,

Chimenti

et al. 2024

The Journal of Pain

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Higher Pain Sensitivity Predicts Efficacy of a Wearable Transcutaneous Electrical Nerve Stimulation Device for Persons With Fibromyalgia: A Randomized Double-Blind Sham-Controlled Trial

Cited by 4 publications

References 56 publications

Efficacy of electrophysical agents in fibromyalgia: A systematic review and network meta-analysis

Efficacy of electrophysical agents in fibromyalgia: A systematic review and network meta-analysis

Optimizing and Accelerating the Development of Precision Pain Treatments for Chronic Pain: IMMPACT Review and Recommendations

Influence of Transcutaneous Electrical Nerve Stimulation (TENS) on Pressure Pain Thresholds and Conditioned Pain Modulation in a Randomized Controlled Trial in Women With Fibromyalgia

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