2023
DOI: 10.34119/bjhrv6n6-167
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Highlights on quinolonic compounds with changes on the basic structure as promising molecules to new drugs

Ana Carolyne Sombra Nery,
Kátia Regina De Souza,
Jorge Luiz de Oliveira Domingos

Abstract: The introduction of quinolonic antimicrobials on the market caused a revolution in antibacterial therapy. 4-quinolone skeleton became the target of many studies of structure-activity relationship establishing the parameters considered optimal for the development of new quinolonic antibiotics. These parameters limited the development of new compounds, so it is possible finding compounds with changes in the same position with similar substituents. The purpose of this article is to identify quinolonic compounds w… Show more

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