Highly biocompatible BSA-MnO2 nanoparticles as an efficient near-infrared photothermal agent for cancer therapy

Wang, Yuzhen; Song, Yujun; Zhu, Guixian; Zhang, Dechen; Liu, Xuewu

doi:10.1016/j.cclet.2017.12.004

Cited by 60 publications

(19 citation statements)

References 36 publications

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“…MnO 2 has been widely used in bioimaging and therapy files due to its unique physicochemical properties. 29 It is easily decomposed in the TME, and the released oxygen can assist Photodynamic therapy (PDT). 30 Meanwhile, the released Mn 2+ has the application of CDT.…”

Section: T H Imentioning

confidence: 99%

In-Situ Assembly of Janus Nanoprobe for Cancer Activated NIR-II Photoacoustic Imaging and Enhanced Photodynamic Therapy

Tang

Chen

et al. 2022

Anal. Chem.

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Inorganic nanoprobes have attracted increasing attention in the biomedical field due to their versatile functionalities and excellent optical properties. However, conventional nanoprobes have a relatively low retention time in the tumor and are mostly applied in the first near-infrared window (NIR-I, 650–950 nm), limiting their applications in accurate and deep tissue imaging. Herein, we develop a Janus nanoprobe, which can undergo tumor microenvironment (TME)-induced aggregation, hence, promoting tumor retention time and providing photoacoustic (PA) imaging in the second NIR (NIR-II, 950–1700 nm) window, and enhancing photodynamic therapy (PDT) effect. Ternary Janus nanoprobe is composed of gold nanorod (AuNR) coated with manganese dioxide (MnO2) and photosensitizer pyropheophorbide-a (Ppa) on two ends of AuNR, respectively, named as MnO2–AuNR-Ppa. In the tumor, MnO2 could be etched by glutathione (GSH) to release Mn2+, which is coordinated with multiple Ppa molecules to induce in situ aggregation of AuNRs. The aggregation of AuNR effectively improves the NIR-II photoacoustic signal in vivo. Moreover, the increased retention time of nanoprobes and GSH reduction in the tumor greatly improve the PDT effect. We believe that this work will inspire further research on specific in situ aggregation of inorganic nanoparticles.

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Section: T H Imentioning

confidence: 99%

In-Situ Assembly of Janus Nanoprobe for Cancer Activated NIR-II Photoacoustic Imaging and Enhanced Photodynamic Therapy

Tang

Chen

et al. 2022

Anal. Chem.

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“…TMDs can be formed with various materials including molybdenum disulfide (MoS 2 ) [ 70 , 71 , 72 , 73 ], tungsten disulfide (WS 2 ) [ 74 , 75 , 76 , 77 ], and molybdenum diselenide (MoSe 2 ) [ 78 , 79 , 80 ]. Transition metal oxides (TMOs) are compounds of oxygen atoms and transition metals such as titanium (TiO 2 ) [ 81 , 82 ] and manganese (MnO 2 ) [ 83 , 84 , 85 ]. Their wide bandgap results in excellent photochemical and electric properties [ 86 , 87 ].…”

Section: Phototherapy Using 2d Nanomaterialsmentioning

confidence: 99%

Recent Trends in Photoacoustic Imaging Techniques for 2D Nanomaterial-Based Phototherapy

et al. 2021

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A variety of 2D materials have been developed for therapeutic biomedical studies. Because of their excellent physicochemical properties, 2D materials can be used as carriers for delivering therapeutic agents into a lesion, leading to phototherapy. Various optical imaging techniques have been used for the monitoring of the treatment process. Among these, photoacoustic imaging has unique advantages including relatively deep imaging depth and large field of view with high spatial resolution. In this review article, we summarize the types of photoacoustic imaging systems used for phototherapy monitoring, then we explore contrast-enhanced photoacoustic images using 2D materials. Finally, photoacoustic image-guided phototherapies are discussed. We conclude that 2D material-based phototherapy can be efficiently monitored by photoacoustic imaging techniques.

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“…162,163 Other inorganic nanomaterials including single-walled carbon nanotubes, carbon dots, MoO 3Àx nanoparticles, and magnetic nanoparticles with broad absorption ranging from UV to NIR can also convert NIR light directly into heat energy for photothermal ablation of mouse tumor xenografts. [164][165][166][167][168][169][170][171][172] In addition, the recent emergence of two-dimensional (2D) nanomaterials provides an original type of PTAs for the maximization of the PTT effect. [173][174][175] For example, the ultrathin MXenes from layered ternary carbides of MAX phases, which served as multifunctional 2D materials prepared by A-element etching methods, were explored for available PTT by Shi's group.…”

Section: Photothermal Therapy (Ptt)mentioning

confidence: 99%

Recent near-infrared light-activated nanomedicine toward precision cancer therapy

et al. 2021

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Highly biocompatible BSA-MnO2 nanoparticles as an efficient near-infrared photothermal agent for cancer therapy

Cited by 60 publications

References 36 publications

In-Situ Assembly of Janus Nanoprobe for Cancer Activated NIR-II Photoacoustic Imaging and Enhanced Photodynamic Therapy

In-Situ Assembly of Janus Nanoprobe for Cancer Activated NIR-II Photoacoustic Imaging and Enhanced Photodynamic Therapy

Recent Trends in Photoacoustic Imaging Techniques for 2D Nanomaterial-Based Phototherapy

Recent near-infrared light-activated nanomedicine toward precision cancer therapy

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