This study examined African higher education students' digital media use for learning. A total of 64 papers were selected for final synthesis from 1046 publications between 2010 and 2021. The review was dominated by campus-based undergraduate studies in the STEM subjects. The synthesis confirmed a variety of digital media usage; however, learning management systems were mainly used for course delivery and primarily accessed by students through weak internet-enabled mobile devices. Digital-media learning activities include communication, information search, instruction, knowledge management, exploration, assessment, collaboration, and simulation. Subject areas were found to have no associations with type of learning activity. These findings suggest an emphasis on transmissive learning modes in digital environments, which may not promote active learning. Although African countries have leapfrogged the development of tethered devices and internet applications, connectivity cost, reported incompatibility, technical issues, and low digital proficiency still prevent the upscaling of technology-enhanced learning via mobile devices.