Highly flexible hydrogel dressing with efficient antibacterial, antioxidative, and wound healing performances

Abstract

Bacterial induced wound infection is very common in real life, but the abuse of antibiotics brings a potential threat to human health. The development of non-antibiotic type antibacterial materials appears...

An agar–polyvinyl alcohol hydrogel loaded with tannic acid with efficient hemostatic and antibacterial capacity for wound dressing

“…The rat wound model of Staphylococcus aureus infection was used to study the wound healing properties of AGAR@PVA–TA hydrogels. 37 Briefly, the circular full-thickness skin wounds (diameter of about 10 mm) were made on the back of the mouse after they were anesthetized by isoflurane. The S. aureus -infected skin wound model were made by inoculating 20 μl of S. aureus suspension (about 1 × 10 8 CFU ml −1 ) onto each wound area.…”

“…The rat wound model of Staphylococcus aureus infection was used to study the wound healing properties of AGAR@PVA-TA hydrogels. 37 Briefly, the circular full-thickness skin wounds…”

A fabricated hydrogel of hyaluronic acid / curcumin shows super-activity to heal the bacterial infected wound

“…Also, hydrogels with characteristics such as porous three-dimensional structure, permeability to oxygen, swelling or liquid absorption, mechanical exibility, and no secondary damage in the wound can be a suitable choice for the new wound dressings development (Liu et al, 2022). Recently, biomedical researchers have focused on the synthesis of antibacterial hydrogels to develop effective wound dressings (Rahmani et al, 2021, Shang et al, 2022. Therefore, in this study for the cutaneous wound healing purpose, we chose crosslinked HA hydrogel.…”

Antibacterial smart hydrogels: New hope for infectious wound management

“…mutans"," E. coli”, “Klebsiella pneumoniae”, and “P. aeruginosa " 2022 [ 299 ] 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO)-doped multifunctional/quaternized carboxymethyl chitosan (QCMCS) and oxidized hyaluronate (HA-CHO) Quaternary ammonium Have a rheological property Exhibit inherent antibacterial and antioxidant properties Have excellent cytocompatibility Reduce the level of hemolysis 2022 [ 300 ] polyethyleneimine (PEI), polyethylene glycol (PEG), hexachlorocyclic triphosphonitrile (HCCP), and gold nanoparticles gold nanoparticles Antibacterial effect against MRSA and S. aureus Show antioxidative activity 2022 [ 301 ] Abbreviations: (ADA) Oxidized alginate; (ADH) adipic acid dihydrazide; (CS) Camellia sinensis; (CSG-PEG); polyethylene glycol monomethyl ether modified glycidyl methacrylate functionalized chitosan; (CHG) Chlorhexidine gluconate; (DMA) methacrylamide dopamine; (Gel-Cat) catechol-modified gelatin; (HA-CHO) oxidized hyaluronate; (HCCP) hexachlorocyclic triphosphonitrile; (Gel-MA/BACA/Cu) Methacrylate modified gelatin and N, N -bis(acryloyl)cystamine-chelated Cu nanoparticles; (KGM) Konjac glucomannan; (OKGM) oxidized Konjac glucomannan; (PN) Pomegranate; (PCDQ) Phosphatidylcholine dihydroquercetin; (PDA@AgNPs); polydopamine decorated silver nanoparticles; (γ-PGA) γ-polyglutamic acid; (PEI) polyethylenimine; (PEG) polyethylene glycol; (QCS-M-PAM) Quaternized chitosan-Matrigel-polyacrylamide; (QCMCS) multifunctional/quaternized carboxymethyl chitosan; (TEMPO) 2,2,6,6-tetramethylpiperidine-1-oxyl-doped. …”