Abstract:Enantioselective Organocatalytic Addition of Nitroalkanes to Oxindolylideneindolenines for the Construction of Chiral 3,3-Disubstituted Oxindoles. -The title addition reaction proceeds in the presence of a cinchona-derived urea as the optically active catalyst to give 3,3-disubstituted oxindoles in high yields and excellent enantioselectivties. Product (IX) is employed for the synthesis of the alkaloid (+)-gliocladin C (X). -(HUANG, J.-Z.; WU, X.; GONG*, L
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.