Highly regio- and stereocontrolled preparation of α-(trifluoromethyl)-β-(phenylthio) enamines by the hydroamination of in situ-synthesized 1-(trifluoromethyl)-2-(phenylthio)ethyne
Akihiro Koga,
Maki Matsuda,
Rin Tanaka
et al.
Abstract:We report the efficient hydroamination of 1-(trifluoromethyl)-2-(phenylthio)ethyne, which proceeds with excellent regio- and stereoselectivity using sulfone amides and azoles.
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