Highly sensitive amperometric creatinine biosensor based on creatinine deiminase/Nafion®-nanostructured polyaniline composite sensing film prepared with cyclic voltammetry

Do, Jing-Shan; Chang, Yang-Chyuan; Tsai, Ming-Liao

doi:10.1016/j.matchemphys.2018.07.057

Cited by 39 publications

(18 citation statements)

References 32 publications

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“…The detection limit for PAni/PET was 1.3 nM, whereas for PPy/PET it was 1.1 nM. Another similar study using electrodeposited ICP utilised CV to deposit a Nafion nanostructured poly(aniline) (PAni) film for the ultrasensitive detection of creatinine(CRN), a common biomarker for nephrological diseases [237]. The film promoted electron transfer and acted as a substrate for creatinine deiminase (CRND) immobilisation.…”

Section: Organic Nanomaterials Applications For Healthcare Biosensingmentioning

confidence: 99%

Nanomaterials for Healthcare Biosensing Applications

Pirzada

Altıntaş

2019

Sensors

188

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In recent years, an increasing number of nanomaterials have been explored for their applications in biomedical diagnostics, making their applications in healthcare biosensing a rapidly evolving field. Nanomaterials introduce versatility to the sensing platforms and may even allow mobility between different detection mechanisms. The prospect of a combination of different nanomaterials allows an exploitation of their synergistic additive and novel properties for sensor development. This paper covers more than 290 research works since 2015, elaborating the diverse roles played by various nanomaterials in the biosensing field. Hence, we provide a comprehensive review of the healthcare sensing applications of nanomaterials, covering carbon allotrope-based, inorganic, and organic nanomaterials. These sensing systems are able to detect a wide variety of clinically relevant molecules, like nucleic acids, viruses, bacteria, cancer antigens, pharmaceuticals and narcotic drugs, toxins, contaminants, as well as entire cells in various sensing media, ranging from buffers to more complex environments such as urine, blood or sputum. Thus, the latest advancements reviewed in this paper hold tremendous potential for the application of nanomaterials in the early screening of diseases and point-of-care testing.

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Section: Organic Nanomaterials Applications For Healthcare Biosensingmentioning

confidence: 99%

Nanomaterials for Healthcare Biosensing Applications

Pirzada

Altıntaş

2019

Sensors

188

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“…Paint [70] Medical [71] Engineering [72] Pharmaceutical sciences [73][74][75] Polymer and polymer films [76] Material sciences…”

Section: Areas Reference For Typical Examplementioning

confidence: 99%

Cyclic Voltammetry and Its Applications

Chooto¹

2019

Voltammetry

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Cyclic voltammetry is a versatile method for scientific investigation and innovation due to the fact that most processes involve electron transfer, which makes them be able to be monitored by this technique. Its uses cover characterization, synthesis, mechanisms, and analysis. In all applications, the technique can work well with a large variety of compounds including organic, inorganic, polymer, films, and semiconductors, among others. Furthermore, the method operates satisfactorily whether in a direct or an indirect approach. It can be considered to be an essential part at the very beginning that leads further to the grand project. As an analytical tool, it plays an important role in not only chemistry but also other involving areas. This review sheds the light on the way the technique proves to become one of the important instruments in research, development, and application labs.

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“…The proton-acceptor properties of PANI contribute to an increase in monovalent permselectivity of perfluorosulfonic acid membranes that can be used for electrodialysis water treatment [46]. A combination of adhesive and conducting properties of PEDOT or PANI with the Nafion selectivity to cations allows the use of com-posites based on them for an improvement in the stability and selectivity of electrochemical sensors [47][48][49][50]. A simple synthesis, mechanical and thermal stability of PANI and PEDOT are important for the mentioned applications.…”

Section: Introductionmentioning

confidence: 99%

Multisensory Systems Based on Perfluorosulfonic Acid Membranes Modified with Polyaniline and PEDOT for Multicomponent Analysis of Sulfacetamide Pharmaceuticals

et al. 2022

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The degradation of sulfacetamide with the formation of sulfanilamide leads to a deterioration in the quality of pharmaceuticals. In this work, potentiometric sensors for the simultaneous determination of sulfanilamide, sulfacetamide and inorganic ions, and for assessing the degradation of pharmaceuticals were developed. A multisensory approach was used for this purpose. The sensor cross-sensitivity to related analytes was achieved using perfluorosulfonic acid membranes with poly(3,4-ethylenedioxythiophene) or polyaniline as dopants. The composite membranes were prepared by oxidative polymerization and characterized using FTIR and UV-Vis spectroscopy, and SEM. The influence of the preparation procedure and the dopant concentration on the membrane hydrophilicity, ion-exchange capacity, water uptake, and transport properties was investigated. The characteristics of the potentiometric sensors in aqueous solutions containing sulfanilamide, sulfacetamide and alkali metals ions in a wide pH range were established. The introduction of proton-acceptor groups and π-conjugated moieties into the perfluorosulfonic acid membranes increased the sensor sensitivity to organic analytes. The relative errors of sulfacetamide and sulfanilamide determination in the UV-degraded eye drops were 1.2 to 1.4 and 1.7 to 4%, respectively, at relative standard deviation of 6 to 9%.

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Highly sensitive amperometric creatinine biosensor based on creatinine deiminase/Nafion®-nanostructured polyaniline composite sensing film prepared with cyclic voltammetry

Cited by 39 publications

References 32 publications

Nanomaterials for Healthcare Biosensing Applications

Nanomaterials for Healthcare Biosensing Applications

Cyclic Voltammetry and Its Applications

Multisensory Systems Based on Perfluorosulfonic Acid Membranes Modified with Polyaniline and PEDOT for Multicomponent Analysis of Sulfacetamide Pharmaceuticals

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