Highly sensitive detection of melamine based on reversed phase liquid chromatography mass spectrometry

Determination of melamine in dairy products by HILIC-UV with NH2 column

“…The strong hydrophilicity of melamine makes its insufficient retention in reversed-phase column, thus ion-pair reagents (such as, sodium octane sulfonate, sodium hexanesulfonate, sodium heptanesulfonate, heptafluorobutyric acid) are usually introduced to enhance its retention and facilitate its separation (Lin, 2009;Sun et al, 2010;Tittlemier, 2010). However, the ion-pair reagents are probably detrimental to the column lifetime, and the low volatility of those reagents also hinders the compatibility with MS detection (Lin, 2009;Sun et al, 2010;Tittlemier, 2010;Wu and Fan et al, 2009). HILIC is a technique in which polar compounds are analyzed on a normal-phase LC column such as silica column.…”

Modern Methodologies to Assess the Olive Oil Quality

“…Exactly in the same period researchers from the University of Shangai have published a mass spectrometric assay of melamine in milk based on the specificity of isotope dilution method by means of a contemporary, reliable and affordable approach. 1 The assessment of quality and safety of all the steps of a given food chain needs to be based on the exploitation of high-tech analytical methodologies. Mass spectrometry represents a…”

Fabrication and Calibration of an Ag Nanoparticles Sensor for Detecting the Melamine and NaCl Levels in Raw Milk

“…There are various effective methods for detecting melamine. [1][2][3][4][5][6][7][8][9] Silver nanoparticles (AgNPs) have been widely used as colorimetric probes for chemical sensing and biosensing due to their unique size-dependent and/or interparticle distance-dependent absorption spectrum and solution color. When the nanoparticles approach each other and aggregate, the color of the nanoparticles changes from yellow to blue for silver nanoparticles, due to the shift of the surface plasmon band to a longer wavelength.…”