Highly sensitive electrochemiluminescent immunosensor based on gold nanoparticles-functionalized zinc oxide nanorod and poly(amidoamine)-graphene for detecting brombuterol

Zhu, Qing; Cai, Fudong; Zhang, Jing; Zhao, Kang; Deng, Anping; Li, Jianguo

doi:10.1016/j.bios.2016.07.091

Cited by 51 publications

(14 citation statements)

References 44 publications

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“…[95] used polyamidoamine dendrimers (PAMAM) and silver-cysteine hybrid nanoribbon (SNR) to prepare CdSe QDS-PAMAM-SNR-Ab for detecting brombuterol in pork and feed. Zhu et al used CdTeQDs-PAMAM-GO-labeled antibody composite to detect brombuterol [96] and used CdSe QDs/PDDA-GN/AuNPslabeled antibody composite to detect ractopamine in pork [97]. The amplification of the ECL signal increased the sensitivity of these ECL immunosensors and decreased the LOD for β 2 -agonist to lower pg/mL level.…”

Section: Electrochemiluminescence Immunosensormentioning

confidence: 99%

Current Advances in Immunoassays for the Detection of β2-Agonists

Ouyang

2022

Foods

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β2-agonists are a group of synthetic phenylethanolamine compounds which are traditionally used for treating bronchospasm. These compounds can also increase skeletal muscle mass and decrease body fat. The illegal use of β2-agonists in food-producing animals results in residue of β2-agonists in edible tissues and causes adverse health effects in humans. Thus, the detection of β2-agonists at trace level in complex sample matrices is of great importance for monitoring the abuse of β2-agonists. Many methods have been developed to detect β2-agonists. Among them, a variety of antigen–antibody interaction-based techniques have been established to detect β2-agonists in various samples, including animal feed, urine, serum, milk, tissues and hair. In this review, we summarized current achievement in the extraction of β2-agonists from testing samples and detection of β2-agonists using immunological techniques. Future perspectives were briefly discussed.

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Section: Electrochemiluminescence Immunosensormentioning

confidence: 99%

Current Advances in Immunoassays for the Detection of β2-Agonists

Ouyang

2022

Foods

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“…Kang et al developed a facile and sensitive method for the detection of CL using a personal glucose meter, suggesting a good linear correlation with the logarithm of the CL concentrations in the range of 0.1–100 ng·mL –1 . A novel ultrasensitive competition-type electrochemiluminescent immunosensor was developed for detecting brombuterol with a low detection limit of 0.3 pg·mL –1 and a wide linear range from 0.001 to 500 ng·mL –1 . Inspired by the merits of electrochemical immunosensors, after the successful preparation of the BSA-RAC-CL-SAL multideterminant antigen and anti-BSA-RAC-CL-SAL antibody, three multiresidue electrochemical immunosensors were constructed in this work to detect six β-agonists CL, SAL, RAC, TER, MAB, and TUL with a new strategy involving nanotechnology, electrochemical detection, and specific immune technology.…”

Section: Introductionmentioning

confidence: 99%

Detection of Six β-Agonists by Three Multiresidue Immunosensors Based on an Anti-bovine Serum Albumin-Ractopamine-Clenbuterol-Salbutamol Antibody

Ren

Zhang

et al. 2020

ACS Omega

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According to an indirect competitive immunoassay, six β-agonists (clenbuterol (CL), salbutamol (SAL), ractopamine (RAC), terbutaline (TER), mabuterol (MAB), and tulobuterol (TUL)) were detected by three novel multiresidue immunosensors on the basis of the successful preparation of bovine serum albumin (BSA)-RAC-CL-SAL multideterminant antigen and anti-BSA-RAC-CL-SAL antibody. A new strategy was reported to detect six β-agonists by combining nanotechnology, electrochemical detection, and specific immune technology. At the same concentration, the amperometric response for detection of six β-agonists was in a sequence of GCE/GNP/SAL > GCE/GNP/RAC > GCE/GNP/CL. Detection limits of six β-agonists show that the multiresidue detection performance of the GCE/GNP/RAC immunosensor is better than those of GCE/GNP/SAL and GCE/GNP/CL immunosensors. Three immunosensors manifest superior properties with a wide linear range, low detection limit, excellent reproducibility, and stability. The proposed GCE/GNP/RAC immunosensor displays high accuracy and can be effectively used for real sample detection.

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“…As one of the mostly widely used metallic NPs, Au NPs possess a variety of excellent physical and chemical properties such as catalysis, optical characteristics, long‐term stability, and easiness in chemical modification, which enables them to be extensively utilized in catalysis chemistry , chemiluminiscence , immunodetection , and separation science . As to separation science, Wang and co‐workers, for example, used Au NPs without any modification to preconcentrate monohydroxy‐polycyclic aromatic hydrocarbons in urine samples .…”

Section: Introductionmentioning

confidence: 99%

A bioinspired polydopamine approach toward the preparation of gold‐modified magnetic nanoparticles for the magnetic solid‐phase extraction of steroids in multiple samples

Xuehan

Chai

Deng

et al. 2018

J of Separation Science

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In this work, a simple, facile, and sensitive magnetic solid-phase extraction method was developed for the extraction and enrichment of three representative steroid hormones before high-performance liquid chromatography analysis. Gold-modified Fe O nanoparticles, as novel magnetic adsorbents, were prepared by a rapid and environmentally friendly procedure in which polydopamine served as the reductant as well as the stabilizer for the gold nanoparticles, thus successfully avoiding the use of some toxic reagents. To obtain maximum extraction efficiency, several significant factors affecting the preconcentration steps, including the amount of adsorbent, extraction time, pH of the sample solution, and the desorption conditions, were optimized, and the enrichment factors for three steroids were all higher than 90. The validity of the established method was evaluated and good analytical characteristics were obtained. A wide linearity range (0.8-500 μg/L for all the analytes) was attained with good correlation (R ≥ 0.991). The low limits of detection were 0.20-0.25 μg/L, and the relative standard deviations ranged from 0.83 to 4.63%, demonstrating a good precision. The proposed method was also successfully applied to the extraction and analysis of steroids in urine, milk, and water samples with satisfactory results, which showed its reliability and feasibility in real sample analysis.

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Highly sensitive electrochemiluminescent immunosensor based on gold nanoparticles-functionalized zinc oxide nanorod and poly(amidoamine)-graphene for detecting brombuterol

Cited by 51 publications

References 44 publications

Current Advances in Immunoassays for the Detection of β2-Agonists

Current Advances in Immunoassays for the Detection of β2-Agonists

Detection of Six β-Agonists by Three Multiresidue Immunosensors Based on an Anti-bovine Serum Albumin-Ractopamine-Clenbuterol-Salbutamol Antibody

A bioinspired polydopamine approach toward the preparation of gold‐modified magnetic nanoparticles for the magnetic solid‐phase extraction of steroids in multiple samples

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