Highly sensitive Escherichia coli shear horizontal surface acoustic wave biosensor with silicon dioxide nanostructures

Ten, Seng Teik; Hashim, U.; Gopinath, Subash C. B.; Liu, Weiwen; Foo, K. L.; Sam, Sung Ting; Rahman, Shaharin Fadzli Abd; Voon, C. H.; Nordin, Anis Nurashikin

doi:10.1016/j.bios.2016.09.035

Cited by 56 publications

(35 citation statements)

References 40 publications

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“…In general, the biosensing aspect [ 161 , 162 , 163 , 164 , 165 , 166 ] of SH-SAW/Love Wave devices remained unexplored for a long time, but during the last few years some promising results have been published which indicates the potential of these devices in biosensors [ 167 ]. SAW-based commercial sensing systems are already in the market for the detection of explosives and narcotics that can be used for screening as well as bulk analysis.…”

Section: Challenges and Opportunitiesmentioning

confidence: 99%

Surface Acoustic Wave (SAW) for Chemical Sensing Applications of Recognition Layers

Mujahid

Dickert

2017

Sensors

147

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Surface acoustic wave (SAW) resonators represent some of the most prominent acoustic devices for chemical sensing applications. As their frequency ranges from several hundred MHz to GHz, therefore they can record remarkably diminutive frequency shifts resulting from exceptionally small mass loadings. Their miniaturized design, high thermal stability and possibility of wireless integration make these devices highly competitive. Owing to these special characteristics, they are widely accepted as smart transducers that can be combined with a variety of recognition layers based on host-guest interactions, metal oxide coatings, carbon nanotubes, graphene sheets, functional polymers and biological receptors. As a result of this, there is a broad spectrum of SAW sensors, i.e., having sensing applications ranging from small gas molecules to large bio-analytes or even whole cell structures. This review shall cover from the fundamentals to modern design developments in SAW devices with respect to interfacial receptor coatings for exemplary sensor applications. The related problems and their possible solutions shall also be covered, with a focus on emerging trends and future opportunities for making SAW as established sensing technology.

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Section: Challenges and Opportunitiesmentioning

confidence: 99%

Surface Acoustic Wave (SAW) for Chemical Sensing Applications of Recognition Layers

Mujahid

Dickert

2017

Sensors

147

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“…In addition, the aptamer was immobilized on the sensitive area by glutaraldehyde (GA) cross-linked chitosan (CS). [42][43][44] The LPS applied in this study was obtained from E. coli 055:B5 (L4524), which was extracted by benzene. Finally, the performance of the biosensor was proven to linearly detect an endotoxin in a wide range from 0 to 100 ng/mL, and the biosensor exhibited a detection limit of 3.53 ng/mL.…”

Section: Introductionmentioning

confidence: 99%

An aptamer-based shear horizontal surface acoustic wave biosensor with a CVD-grown single-layered graphene film for high-sensitivity detection of a label-free endotoxin

Pang

et al. 2020

Microsyst Nanoeng

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The thickness of the sensitive layer has an important influence on the sensitivity of a shear horizontal surface acoustic wave (SH-SAW) biosensor with a delay-line structure and lower layer numbers of graphene produce better sensitivity for biological detection. Therefore, a label-free and highly sensitive SH-SAW biosensor with chemical vapor deposition (CVD-)-grown single-layered graphene (SLG) for endotoxin detection was developed in this study. With this methodology, SH-SAW biosensors were fabricated on a 36°Y-90°X quartz substrate with a base frequency of 246.2 MHz, and an effective detection cell was fabricated using acrylic material. To increase the surface hydrophilicity, chitosan was applied to the surface of the SLG film. Additionally, the aptamer was immobilized on the surface of the SLG film by cross-linking with glutaraldehyde. Finally, the sensitivity was verified by endotoxin detection with a linear detection ranging from 0 to 100 ng/mL, and the detection limit (LOD) was as low as 3.53 ng/mL. In addition, the stability of this type of SH-SAW biosensor from the air phase to the liquid phase proved to be excellent and the specificity was tested and verified by detecting the endotoxin obtained from Escherichia coli (E. coli), the endotoxin obtained from Pseudomonas aeruginosa (P. aeruginosa), and aflatoxin. Therefore, this type of SH-SAW biosensor with a CVD-grown SLG film may offer a promising approach to endotoxin detection, and it may have great potential in clinical applications.

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“…Some special piezoelectric crystals with a special cut can excite shear horizontal (SH) surface acoustic waves (SAWs), which are very good for liquid and biological SAW sensors. (1)(2)(3)(4)(5)(6)(7)(8)(9)(10) SAW sensors are based on the mass loading effect. Therefore, a high SAW velocity will make SAW sensors work at a high frequency to have a high sensitivity.…”

Section: Introductionmentioning

confidence: 99%

High-shear-velocity Composite Acoustic Materials of AlN/Diamond for Biological MEMS Devices

Huang¹,

Wu²

2019

Sensors and Materials

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Shear horizontal (SH) surface acoustic wave (SAW) sensors formed by combining (100) AlN films with a diamond substrate have been developed in this research. The propagation characteristics of SAW in four composite structures according to the positions of interdigital transducer (IDT) electrodes and/or thin metal films were investigated theoretically. Those composite SAW substrates exhibited excellent SH SAW properties and have the potential for further application in biological and liquid SAW sensors.

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Highly sensitive Escherichia coli shear horizontal surface acoustic wave biosensor with silicon dioxide nanostructures

Cited by 56 publications

References 40 publications

Surface Acoustic Wave (SAW) for Chemical Sensing Applications of Recognition Layers

Surface Acoustic Wave (SAW) for Chemical Sensing Applications of Recognition Layers

An aptamer-based shear horizontal surface acoustic wave biosensor with a CVD-grown single-layered graphene film for high-sensitivity detection of a label-free endotoxin

High-shear-velocity Composite Acoustic Materials of AlN/Diamond for Biological MEMS Devices

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