Highly sensitive luminol electrochemiluminescence immunosensor based on ZnO nanoparticles and glucose oxidase decorated graphene for cancer biomarker detection

Zinc oxide nanoparticle-enhanced ultrasensitive chemiluminescence immunoassay for the carcinoma embryonic antigen

“…The interface formed due to binding between an oxide nano-material and a [27] biomolecule can influence the performance of an immunosensor. The formation and properties of a nano -bio interface depends upon the nature of nano-structure parameters like surface charge, valence/conductance states, functional groups, physical states and hygroscopic nature [16].…”

A nanoporous palladium-nickel alloy with high sensing performance towards hydrogen peroxide and glucose

“…Consequently, development of highly sensitive, accurate, and selective method for determination of H 2 O 2 and glucose is of significant importance in food, pharmaceutical, industrial, and environmental analyses. Different analytical methods for the detection of H 2 O 2 and glucose have been reported, such as colorimetric assay, fluoroimmunoassay, and electrochemiluminescence [9][10][11]. Among these methods, electrochemical sensors based on electrooxidation of small molecules have gained remarkable attention owing to the advantages of convenient operation, fast response time, and low cost [12][13][14][15].…”

Immunosensing procedures for carcinoembryonic antigen using graphene and nanocomposites

“…The combination of aptamers and peroxidase-like activity NPs could be envisioned as one of the best combinations. It should be noted that electrochemiluminescence of luminol is enhanced by ZnO nanoparticles, which forms the basis for a novel immune assay scheme for CEA (Cheng et al, 2012). However, the system is not completely free from enzyme since glucose oxidase is used to label the detection antibody to generate H 2 O 2 in situ.…”

“…(Cheng et al, 2012) The analytical performance is evaluated by adding CEA to normal serum sample. The recovery ranges from 86 to 108 %.…”