Highly sensitive mid-infrared SPR biosensor for a wide range of biomolecules and biological cells based on graphene-gold grating

Sadeghi, Zeynab; Shirkani, Hossein

doi:10.1016/j.physe.2020.114005

Cited by 36 publications

(13 citation statements)

References 46 publications

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“…In the refractive index change

= 0.001 from 1.333 to 1.334, the resulting SPR biosensor sensitivity is 1450 nm/RIU. After the optimization process, the best SPR sensitivity generated in this structure is 1782 nm/RIU [ 74 ]. Sadeghi and Shirani also investigated the performance of the SPR biosensor on rectangular gratings.…”

Section: Graphene Based Grating Coupled Spr Biosensormentioning

confidence: 99%

See 1 more Smart Citation

A Review of Graphene-Based Surface Plasmon Resonance and Surface-Enhanced Raman Scattering Biosensors: Current Status and Future Prospects

Nurrohman

Chiu

2021

Nanomaterials

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The surface plasmon resonance (SPR) biosensor has become a powerful analytical tool for investigating biomolecular interactions. There are several methods to excite surface plasmon, such as coupling with prisms, fiber optics, grating, nanoparticles, etc. The challenge in developing this type of biosensor is to increase its sensitivity. In relation to this, graphene is one of the materials that is widely studied because of its unique properties. In several studies, this material has been proven theoretically and experimentally to increase the sensitivity of SPR. This paper discusses the current development of a graphene-based SPR biosensor for various excitation methods. The discussion begins with a discussion regarding the properties of graphene in general and its use in biosensors. Simulation and experimental results of several excitation methods are presented. Furthermore, the discussion regarding the SPR biosensor is expanded by providing a review regarding graphene-based Surface-Enhanced Raman Scattering (SERS) biosensor to provide an overview of the development of materials in the biosensor in the future.

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“…In the refractive index change

Section: Graphene Based Grating Coupled Spr Biosensormentioning

confidence: 99%

“…( b ) The intensity distribution of the electromagnetic field at maximum wavelength of SPR mode. ( c ) SPR sensitivity investigations based on the shift in peak wavelength on the extinction curve (adapted with permission from Reference [ 74 ], copyright Elsevier).…”

Section: Figurementioning

confidence: 99%

A Review of Graphene-Based Surface Plasmon Resonance and Surface-Enhanced Raman Scattering Biosensors: Current Status and Future Prospects

Nurrohman

Chiu

2021

Nanomaterials

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“…It is declared that, by managing and engineering tunable properties of graphene-based nano-structures, they can be effectively used as biosensors for different applications [ 23 ]. In another research, graphene-gold combination structure is proposed for detecting bio-molecules and biological cells like blood, glucose, and other elements, considering their refractive indices [ 24 ].…”

Section: Introductionmentioning

confidence: 99%

Sensitive Hemoglobin Concentration Sensor Based on Graphene-Plasmonic Nano-structures

2021

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In this paper, half-cylindrical-shaped rods are arranged in a row in order to form hemoglobin concentration sensors. The proposed structures can effectively detect hemoglobin concentrations in blood samples. Five individual structures based on graphene-plasmonic combinations are proposed and investigated. The proposed structures are made of different layers of Au, Ag, SiO 2 , and graphene. Different plates and cylindrical-shaped graphene layers are introduced in the structures to improve the functionality (absorption peak value and wavelength) of the absorber (sensor). Adding more Au layers strengthens the confinement of the incident electromagnetic waves and improves the absorption factor. Also, in the proposed structures, for improving the results, the effects of the chemical potential of graphene layers and “G” (graphene layer thicknesses) on the absorption peak and wavelength are considered. The final suggested structure indicates unity absorption peak and thus can be utilized in wide ranges of applications. As a refractive index bio-sensor, the structure is considered for detecting hemoglobin concentrations in blood samples which indicates a reasonable sensitivity factor of 570 nm/RIU.

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“…Sadeghi et al proposed a graphene-gold ellipse grating SPR biosensor. They claimed that a sensitivity of 1782 nm/RIU and a quality factor of 21,214 were obtained for a refractive index 1.333 [17]. Research into biosensors is still progressing.…”

Section: Introductionmentioning

confidence: 99%

Theoretical Model for a Highly Sensitive Near Infrared Biosensor Based on Bloch Surface Wave with Dirac Semimetal

Zheng

Dai

et al. 2021

Biosensors

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In this work, we present a theoretical model of a near-infrared sensitive refractive index biosensor based on the truncate 1D photonic crystal (1D PC) structure with Dirac semimetal. This highly sensitive near-infrared biosensor originates from the sharp reflectance peak caused by the excitation of Bloch surface wave (BSW) at the interface between the Dirac semimetal and 1D PC. The sensitivity of the biosensor model is sensitive to the Fermi energy of Dirac semimetal, the thickness of the truncate layer and the refractive index of the sensing medium. By optimizing the structural parameters, the maximum refractive index sensitivity of the biosensor model can surpass 17.4 × 103/RIU, which achieves a certain competitiveness compared to conventional surface plasmon resonance (SPR) or BSW sensors. Considering that bulk materials are easier to handle than two-dimensional materials in manufacturing facilities, we judge that 3D Dirac semimetal and its related devices will provide a strong competitor and alternative to graphene-based devices.

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Highly sensitive mid-infrared SPR biosensor for a wide range of biomolecules and biological cells based on graphene-gold grating

Cited by 36 publications

References 46 publications

A Review of Graphene-Based Surface Plasmon Resonance and Surface-Enhanced Raman Scattering Biosensors: Current Status and Future Prospects

A Review of Graphene-Based Surface Plasmon Resonance and Surface-Enhanced Raman Scattering Biosensors: Current Status and Future Prospects

Sensitive Hemoglobin Concentration Sensor Based on Graphene-Plasmonic Nano-structures

Theoretical Model for a Highly Sensitive Near Infrared Biosensor Based on Bloch Surface Wave with Dirac Semimetal

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