Highly Sensitive Voltammetric Sensor for Nanomolar Dopamine Detection Based on Facile Electrochemical Reduction of Graphene Oxide and Ceria Nanocomposite

Abstract

In this study, a new electrochemical sensor was fabricated and characterized based on a glassy carbon electrode (GCE) modified with ceria (CeO 2 ) nanoparticles decorated with electrochemical reduced graphene oxide (denoted as Ceria-ErGO/GCE). The results showed that a large number of spherical ceria nanoparticles with a diameter of 20-200 nm are well wrapped by gossamer like ErGO nanosheets. Compared with ceria and ErGO, ceria-ErGO nanocomposites have a synergistic effect on the charge transfer between the electrode and the solution interface. Ultrasensitive and selective determination of dopamine (DA) can be realized at the Ceria-ErGO/GCE. Under the optimum conditions, the calibration curve for the peak current of DA oxidation vs its concentration showed in three fragmented ranges of 6.0 nM-0.1 μM; 0.1 μM-2.0 μM and 2.0 μM-20 μM, respectively. The limit of detection of 3.0 nM (S/N = 3) was obtained under 90 s accumulation. In addition, the advantages of the sensor are easy regeneration of electrode surface, fast and convenient electrode preparation, low cost, sensitive and reliable determination results. This method is particularly suitable for the fast detection of DA in commercial pharmaceuticals and clinical urine as well as serum samples.

ZnO–ZnFe2O4/Fe3O4/Carbon Nanocomposites for Ultrasensitive and Selective Dopamine Detection

“…Indeed, the lowest detectable [DA] and the slope of the calibration improved significantly with DPV analysis (Figure C,D). This lowered the LOD down to 1.57 nM, which is ∼2 times lower than that of the recently reported high-performing ceria-ErGO/GCE . The 1.57 nM value is by far the lowest LOD ever reported for Fe 3 O 4 -based materials, to the best of our knowledge.…”

“…This lowered the LOD down to 1.57 nM, which is ∼2 times lower than that of the recently reported high-performing ceria-ErGO/GCE. 59 The 1.57 nM value is by far the lowest LOD ever reported for Fe 3 O 4 -based materials, to the best of our knowledge. However, it still falls short of the picomolar LOD reported for postdeposition annealed graphene ink.…”

An Electrochemical Sensor Based on a Nitrogen-Doped Carbon Material and PEI Composites for Sensitive Detection of 4-Nitrophenol

“…In recent years, due to its advantages of eco-friendliness, high sensitivity, good selectivity and low cost, an electrochemical method has been widely used in the determination of pollutants, small biomolecules, food additives and heavy metal ions [ 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 ]. A molecule with high electrochemical activity, 4-NP can be easily reduced in the process of an electrochemical reaction.…”

Low‐temperature preparation and photoelectrochemical properties of TiO2 nanotubes‐graphene‐CNT hybrid structure

“…By reviewing the literature, this method has been employed to prepare various organic and inorganic‐carbon material hybrids by using silica, alumina, magnesium oxide, calcium carbonate, and molybdenum‐transition bimetal catalyst 41‐53 . The nature of support and its morphology strongly influence the morphology and quality of the prepared material.…”

“…By reviewing the literature, this method has been employed to prepare various organic and inorganic-carbon material hybrids by using silica, alumina, magnesium oxide, calcium carbonate, and molybdenum-transition bimetal catalyst. [41][42][43][44][45][46][47][48][49][50][51][52][53] The nature of support and its morphology strongly influence the morphology and quality of the prepared material. Actually, the strong interaction between the catalyst surface and carbon material is necessary for the preparation of high-quality product.…”