Highly stable and regenerative graphene–diamond hybrid electrochemical biosensor for fouling target dopamine detection

Yuan, Qilong; Liu, Ying; Wang, Hongzhi; Sun, Hongyan; Dang, Dai; Wei, Qiuping; Lai, Guosong; Wu, Tianzhun; Yu, Aimin; Fu, Li; Chee, Kuan W. A.; Lin, Cheng‐Te

doi:10.1016/j.bios.2018.04.006

Cited by 125 publications

(39 citation statements)

References 50 publications

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“…DNA sensors modified to detect metal ions such as Hg 2+ were reported. Nucleic acid-based biosensors are widely used in molecular diagnosis ( Liu et al, 2017 ), pathology ( Cagnin et al, 2009 ), toxicology ( Chen et al, 2016 ), and molecular sequencing ( Yuan et al, 2018 ). Among those, G-quadruplex based biosensor has also been used for analysis and detection of different targets recently ( Table 1 ).…”

Section: G-quadruplex Based Biosensormentioning

confidence: 99%

G-quadruplex based biosensor: A potential tool for SARS-CoV-2 detection

Juhas

Zhang

2020

Biosensors and Bioelectronics

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G-quadruplex is a non-canonical nucleic acid structure formed by the folding of guanine rich DNA or RNA. The conformation and function of G-quadruplex are determined by a number of factors, including the number and polarity of nucleotide strands, the type of cations and the binding targets. Recent studies led to the discovery of additional advantageous attributes of G-quadruplex with the potential to be used in novel biosensors, such as improved ligand binding and unique folding properties. G-quadruplex based biosensor can detect various substances, such as metal ions, organic macromolecules, proteins and nucleic acids with improved affinity and specificity compared to standard biosensors. The recently developed G-quadruplex based biosensors include electrochemical and optical biosensors. A novel G-quadruplex based biosensors also show better performance and broader applications in the detection of a wide spectrum of pathogens, including SARS-CoV-2, the causative agent of COVID-19 disease. This review highlights the latest developments in the field of G-quadruplex based biosensors, with particular focus on the G-quadruplex sequences and recent applications and the potential of G-quadruplex based biosensors in SARS-CoV-2 detection.

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Section: G-quadruplex Based Biosensormentioning

confidence: 99%

G-quadruplex based biosensor: A potential tool for SARS-CoV-2 detection

Juhas

Zhang

2020

Biosensors and Bioelectronics

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“…When graphene film completely blocked the contact between HPHT and copper, the entire catalytic reaction ended. As a result, a HPHT substrate with graphene surface was obtained, which can be used as a highly stable and regenerative electrode after encapsulation (Figure 1B,C,D) [12].…”

Section: Resultsmentioning

confidence: 99%

Electrochemical Enantiomer Recognition Based on sp3-to-sp2 Converted Regenerative Graphene/Diamond Electrode

et al. 2018

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It is of great significance to distinguish enantiomers due to their different, even completely opposite biological, physiological and pharmacological activities compared to those with different stereochemistry. A sp3-to-sp2 converted highly stable and regenerative graphene/diamond electrode (G/D) was proposed as an enantiomer recognition platform after a simple β-cyclodextrin (β-CD) drop casting process. The proposed enantiomer recognition sensor has been successfully used for d and l-phenylalanine recognition. In addition, the G/D electrode can be simply regenerated by half-minute sonication due to the strong interfacial bonding between graphene and diamond. Therefore, the proposed G/D electrode showed significant potential as a reusable sensing platform for enantiomer recognition.

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“…Hence, a hybrid electrode with strong interfacial adhesion was developed using diamond and graphite. The electrode was investigated in the linear range of 5 μM–2 mM with a limit of detection of 200 nM . Photoelectrochemical sensors based on tremella such as ZnIn 2 S 4 /graphene composite were proposed.…”

Section: Sensors and Biosensorsmentioning

confidence: 99%

Electrochemical Sensors and Biosensors Based on Graphene Functionalized with Metal Oxide Nanostructures for Healthcare Applications

et al. 2019

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Graphene has attracted wide consideration in recent years to the assembly of sensitive sensors and biosensors due to its unique and remarkable physical and electrochemical properties. Moreover, graphene, as an essential two‐dimensional carbon material with remarkably high quartz and electronic superiority, has also received significant research attention. This review presents the different synthesis techniques of graphene; graphene functionalized based electrochemical sensors and biosensors for various health care appellations. Further, were discussed on the basis of enhanced catalytic activity, improved detection limit in conjunction with sensitivity, and selectivity. Synergistic action of graphene and metal oxide nanostructure has contributed towards high activity as a biosensing material. The results with different sensors and biosensors for the detection of significant biomarkers such as protein sensor, electrochemical immune sensor, phytochrome sensor, cholesterol biosensor glucose, hydrogen peroxide, and nicotinamide adenine dinucleotide detection sensor etc., and highlighted the use of graphene and functionalized graphene in different sensing platforms. Finally, the challenges related to less aggregated graphene‐based electrochemical sensors and biosensors as well as future research directions are discussed.

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Highly stable and regenerative graphene–diamond hybrid electrochemical biosensor for fouling target dopamine detection

Cited by 125 publications

References 50 publications

G-quadruplex based biosensor: A potential tool for SARS-CoV-2 detection

G-quadruplex based biosensor: A potential tool for SARS-CoV-2 detection

Electrochemical Enantiomer Recognition Based on sp3-to-sp2 Converted Regenerative Graphene/Diamond Electrode

Electrochemical Sensors and Biosensors Based on Graphene Functionalized with Metal Oxide Nanostructures for Healthcare Applications

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