Highly Uniform and Reproducible Surface Enhanced Raman Scattering on Air-stable Metallic Glassy Nanowire Array

Abstract

Preparation of surface enhanced Raman scattering (SERS) nanostructures with both high sensitivity as well as high reproducibility has always been difficult and costly for routine SERS detection. Here we demonstrate air-stable metallic glassy nanowire arrays (MGNWAs), which were prepared by a cheap and rapid die nanoimprinting technique, could exhibit high SERS enhancement factor (EF) as well as excellent reproducibility. It shows that Pd40.5Ni40.5P19 MGNWA with nanowires of 55 nm in diameter and 100 nm in pitch possesses high SERS activity with an EF of 1.1 × 105, which is 1–3 orders of magnitudes higher than that of the reported crystal Ni-based nanostructures, and an excellent reproducibility with a relative standard deviation of 9.60% measured by 121 points over an area of 100 μm*100 μm. This method offers an easy, rapid, and low-cost way to prepare highly sensitive and reproducible SERS substrates and makes the SERS more practicable.

A low-cost, monometallic, surface-enhanced Raman scattering-functionalized paper platform for spot-on bioassays

“…A 2-μL M a n u s c r i p t -9 -aliquot of 1 mM RhB (probe molecule of Raman spectroscopy) was dropped onto the SERS-active area to determine the optimal condition of the CMC-AuNP ink. The dominant Raman peaks of RhB were measured at 620 cm -1 (aromatic bending), 1201 cm -1 (aromatic C-H bending), and 1356 cm -1 (aromatic C-C stretching) [9]. The prominent Raman peak at 1356 cm -1 was selected as the reference peak of RhB analysis.…”

“…A spot is the size of the substrate, and A laser is the size of the laser spot [8,9]. Since the same methods for assessing the Raman measurement were applied to two substrates, the parameters of N A of RhB, V, A spot , and A laser were the same.…”

“…Raman spectroscopy is a technique to provide molecule-specific information on biological and chemical samples [1][2][3].…”

“…The enhancement factor (EF), which is used as a measure of the magnitude of SERS, is commonly in the range of 10 4 -10 8 and can be as high as 10 14 , allowing for detection at the single-molecule level [6]. Most studies aiming to increase the SERS EF have concentrated on substrate-related issues by modifying the materials and nanostructure patterns of the surface [7][8][9][10][11]. Most SERS-active areas are fabricated using complex and sophisticated methods including lithography or a high-temperature process.…”

Rapid label-free identification of Klebsiella pneumoniae antibiotic resistant strains by the drop-coating deposition surface-enhanced Raman scattering method

“…where N A is Avogadro's constant, c is the concentration of the probe molecule, V is the volume of the molecule droplet, A spot is the substrate size, and A laser is the laser spot size [35]. Since the same methods for assessing the Raman measurement were applied to the two substrates, the parameters of N A for R6G, V, A spot , and A laser were the same.…”